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Spongiform Encephalopathy Case Study

Decent Essays

Prion proteins are able to cause bovine spongiform encephalopathy (Mad cow disease)through conformational changes in the protein structure. Discuss these changes and how the disease results from such changes.

The infectious agent in BSE is accepted to be a particular sort of misfolded protein called a prion. Prions won't vanish regardless of the fact that the meat containing them is cooked. Prion proteins convey the ailment in the middle of people and cause crumbling of the cerebrum.

BSE is a kind of transmissible spongiform encephalopathy (TSE). TSEs can emerge in creatures that convey an allele which causes beforehand ordinary protein particles to bend independent from anyone else from an alpha helix course of action to a beta sheet, which

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