Hemophilia is term coined by Johann Schönlein is derived for Greek and Latin words that refer to one who loves to bleed or hemorrhage (Carson-DeWitt, 2014). Hemophilia is a disorder in the body's mechanism of clotting. In simpler terms, people afflicted with hemophilia have a risk of bleeding out from minor injuries.
Hemophilia A is an X-linked disorder caused by a deficient or defective clotting factor VIII (FVIII) protein, and characterized by spontaneous or traumatic bleeding into joints and muscles [Ragni]. It causes afflicted individuals to not be able to coagulate their blood very efficiently or at all when getting an injury in which blood is exposed either internally or externally. This disease can be very dangerous and fatal because major blood loss can occur if the patient has not received treatment.
This kind of bleeding is very painful and may lead to joint deformity and arthritis. As the person with hemophilia experiences episodes, they are better to identify “a bleed” before there are any outward signs. For instance; As blood collects in the joint or muscle space, they may notice warmth, pain, and/or swelling to the area affected. For an infant or toddler the caretaker may notice some signs and symptoms suck as, swelling and warmth to an area of the body, blood in the urine or stool, unexplained irritability, or pain (“hemophilia”2002).
Hemophilia is a genetic bleeding disorder that slows down the clotting process of one’s blood. There are two types of the disorder: hemophilia A and hemophilia B. Both result in very similar symptoms, however, they are caused by different mutations of genes on the X chromosome. The way in which the disorder is inherited is known as an “X-linked recessive pattern.” Since males only have one X chromosome, one gene mutation is all that is needed in order to obtain hemophilia. On the other hand, females have two X chromosomes meaning that two mutations (on on each X chromosome) are required to inherit hemophilia. For that reason, it’s far more unlikely for females to have hemophilia than it is for males. Specifically, the genes which cause
First described by Babylonian Jews more than 1700 years ago (NCBI, 2011), hemophilia A has been considered a very interesting genetic disease ever since. In addition, hemophilia A gained widespread attention after Queen Victoria transmitted the disease to several royal families in Europe (NCBI, 2011). As scientists gain more knowledge regarding this genetic disease, more effective treatments have emerged as a result.
In 1903 Rasputin's wanderings brought him to St. Petersburg, where he arrived with a reputation as a mystic and faith healer. Two years later he was introduced to Russian Czar Nicholas II and his wife Alexandra Feodorovna, They were seeking help for their sick son, Alexis. Rasputin gained their confidence by "curing" the boy of hemophilia. This action won him the support of Alexandra. As Russia entered World War I Rasputin predicted that the country would fall. Nicholas II took command of the Russian Army in 1915. Alexandra was always Rasputin's defender, she refused ministers who were said to be suspicious of the "mad monk." Government officials tried to warn her of Rasputin's bad behavior, but she continued to defend him. On the night of
Hemophilia is a possible cause of unexpected bleeding during surgery. This paper will discuss important topics related to hemophilia, including pathology, risk factors, signs and symptoms, and treatment.
To test for the diagnosis, you must get the testing done when you are first born or a person can get the disease when you are older so people may want to do a test every 10 years. The testing is done with a blood test they prick your finger to draw some blood and put the blood sample under a microscope to
According to the CDC website, Hemophilia, is a hereditary bleeding disorder which affects mostly males due to X chromosome singularity. Hemophilia is a medical condition in which the blood clotting becomes a challenge for those affected. Symptoms include spontaneous bleeding from injuries or surgery. Blood contains many proteins called clotting factors that assist in blood coagulation, however; those individuals with hemophilia have low levels of either factor VIII or factor IX. The severity of the condition is determined by the amount of factor in the blood thus the lower the amount of the factor, the higher the chances that spontaneous bleeding will occur leading to more severe health complications.
A. It 's important to know that hemophilia is not actually a disease or virus. https://my.clevelandclinic.org calls hemophilia "a rare hereditary (inherited) bleeding disorder in which blood cannot clot normally at the site of a wound or injury". This means that it is not contagious, rather it is passed down through genetics. When a hemophiliac gets injured,
This testing can be done through various processes. Many go through the usual tests that get blood and tissue samples from your body so it can be analyzed. There are also those that perform genetic tests, especially if you have a history in the family with this disease. If you are a woman, you might also undergo mammogram or a pap smear.
A genetic disorder that affects the blood vessels when injured that results in clotting is Hemophilia. This inherited disorder is not contagious and is found through various lab tests such as a blood clotting test. The way someone can be aware if they could encounter Hemophilia is simply by viewing their medical history,
Hemophilia is a problem with the blood in a person that causes them to bleed not any faster than normal, but they often bleed for a longer period. Their blood is missing the clotting factor (a protein in the bloodstream that works to control bleeding). Hemophilia is quite rare; roughly 1 in every 10,000 persons are born with it. Rarely, hemophilia can be an acquired disease which just means a person is not born with it, but will develop it during their lifetime. This rarity occurs when a person's immune system forms antibodies that attack the clotting factor in the blood. The entire antibody population fights against the blood to prevent the clotting factors from working properly.