With a huge number of victims, 80 to 100 million, since 1918, the influenza is considered as one of the most pandemic diseases ever. There are three types of influenza virus: influenza virus A, influenza virus B, and influenza virus c. These are a subtypes of the virus family orthomyx-oviride. The types B and C do not cause pandemic diseases while type A does. The type A classified into three main subtype H1.N1, H1.N2, and H3.N2. The (H.N) refers to the two kinds of proteins on the surface of the virus (hemagglutinin and neuraminidase). The difference in numbers is due to the difference in protein variability. A H1.N1 virus which is widely known as Spanish flu is the only type that can transmit from human to human. The H5.N1, or “bird flu” …show more content…
The fastest communication of the virus to humans were reported in turkey. Simultaneously, 1.5 million birds were killed to contain the virus. The symptoms of such a disease that the temperature of your body dramatically starts to increase followed by a cough. Then the host (humans) starts to experience a difficulty in breathing and a severe pain in the stomach most of it ends with diarrhea – a disease happens when our digestive system are not able any more to absorb liquids and minerals. A further exposure to the virus can lead to shock, the respiratory system stop working completely, and the other vital organs like liver fail to function normally and eventually death may occur.
As already mentioned, the H5.N1 is a subtype of an influenza A type. This type consists of RNA. This RNA names as HA and NA. The HA is glycoproteins found on the surface of the virus. This special protein helps the virus to bind to the host cell. While NA is glycosylated enzyme sits on the surface as well. It helps to release the virus from the host cell. In reality, the least pathogenic virus is H5.N1 or (LPAI H5N1), is commonly happening in wild birds for example, in 1983 it is reported that the virus being carried by the ring-billed gulls in Pennsylvania, ( Bird flu (H5.N1) Genetic in news-medical). The virus itself cannot be pathogenic unless some changes occur, which means new progeny. When the RNA of two viruses enters a combination process in the host cell.
There are there types of influenza A and C or the most severe types and B which is the most common, Luckily not the to severe. The virus works by first attaching to the outside of a host cell. It injects its RNA into the cell. Unfortunately our cells treat the RNA like they should. It translates the viral genes using the cell’s ribosomes and enzymes. Now the virus can take the cell over and use it to reproduce more viruses. Sooner or later it releases the new nauseating viruses and they search for another cell to raid.
Avian influenza is a disease that has been wreaking havoc on human populations since the 16th century. With the recent outbreak in 1997 of a new H5N1 avian flu subtype, the world has begun preparing for a pandemic by looking upon its past affects. In the 20th Century, the world witnessed three pandemics in the years of 1918, 1957, and 1968. In 1918 no vaccine, antibiotic, or clear recognition of the disease was known. Killing over 40 million in less than a year, the H1N1 strain ingrained a deep and lasting fear of the virus throughout the world. Though 1957 and 1968 brought on milder pandemics, they still killed an estimated 3 million people and presented a new
The short-term effects on a singular human for this virus would be a high fever, chills, headaches, severe back pain, vomiting and abdominal pain. The short-term effects on the whole human race would not be extremely dangerous until it begins to mutate to become more transmissive. The long-term effects on a singular person would be severe organ failure as well as the previous effects and also immune suppression of their immune system. The long-term effects on the whole human race would be extreme infection worldwide with easily over half of the world infected. The final impacts on the human race would be
Structure: The influenza virus looks like a sphere covered with spike like proteins for grip ready to latch on to a healthy human cell. “The H spike (hem agglutinin) and the N spike (neuraminidase) are called proteins and exist in the envelope and they are used for antigenic typing” (Pearson 2004). These proteins allow the virus to enter and exit the host (our cells). Once the virus is inside the cell, the virus can begin reproducing. Soon, each infected cell is filled with thousands of new viruses, each of them looking to leave the cell to find a new home in another cell and begin reproducing there.
This season has witnessed the presence and impact that two flu strains, the A-H1N1, and the A-H3N2, but it is the A-H3N2 that is the main culprit guilty of causing the majority of influenza incidents this season. The A-H3N2 is noted by the Centers for Disease Control and Prevention (CDC) as being linked to serious ailment in people over 65 and young kids, with at-risk kids being those under the age of 2. It is a rapidly mutating virus and is capable of evading vaccine, which is characterized as being 30% effective against the A-H3N2 strain. This means that this virus is nastier, capable of sending more people to the hospital, complicating underlying conditions, and causing more deaths.
In the article “Avian Influenza: An Agricultural Perspective,” Andrea Morgan (2006) researched the impact avian influenza has on different parts of the world. In her research she realized that the most harmful pandemic of the disease was the “Spanish influenza” which affected 50 million people worldwide. The strain of avian influenza Morgan based her research around was the H5N1 influenza A, which is found in poultry. She researched how fast the influenza can be transmitted and who it affected worldwide. In order to prevent the spread of influenza in the United States, the United States Department of Agriculture (USDA) follows specific measures to ensure that they do not contain the outbreak (Morgan, p. 139). Influenza is most commonly found in birds, but it can also be transmitted to swine causing it to be more easily developed in humans. Which leads to research done by Piaggio, Clark, Franklin, and
Influenza A, B, and C viruses are responsible for epidemics in humans. They are “characterized by a segmented, single-stranded ribonucleic acid (RNA) genome” (Grossman & Porth, 2014, p. 932). The influenza A virus contains 2 subtypes: hemagglutinin
The Avian Influenza virus also known as Bird flu is a disease that infects birds such as, chickens, turkeys, ducks, and geese. Symptoms of the infection are respiratory disease, unable to produce eggs, and fatality. Usually the symptoms are unnoticeable. There are two main types of Asian Influenza is LPAI and HPAI. LPAI is low pathogenicity meaning birds are not as likely to die from the virus. HPAI H5 is highly pathogenic, more severe and has a higher mortality rate. Outbreaks of this disease started in Europe and Asian. In 2015 there has been reports that AI has infected poultry in the United States.
As it turns out, H5N1 (avian influenza) is a type of influenza A. While influenzas B and C only affect humans, influenza A can affect all kinds of animals as well as humans. Influenza B one of the more common types of flu and is usually associated with coughing and soreness. Influenza C is the most common and its symptoms are so mild that it can pass as a normal cold. The least common and most severe, is obviously influenza A. Influenza A is constantly changing and evolving so thats why scientists are keeping a close eye on it. All types of influenza A, not just H5N1, are at risk of becoming another flu epidemic. The virus is on the verge of being able to pass from person to person. Right now, the solution is to kill all the infected animals and burn them. What are we going to do when it starts passing from animals to humans, and then to other humans? We can’t just kill all the infected humans and hope it goes away. Scientists are trying to stop the viruses before they start evolving and transmitting in new
The influenza virus is an RNA virus has an envelope that included members of the family Orthomyxoviridae. Its genome is a single negative strand segmented RNA. This virus consists of three types: A, B, and C. Influenza types A and B has eight segments of RNA, but the influenza virus type C only has 7
A disease that can affect numerous species ranging from humans to birds and even swine is the influenza virus (Kapoor and Dhama 2014). The influenza virus is separated into three genera; A, B, C (Kapoor and Dhama 2014). While all three types of influenza have their own effects on different populations the one that is mostly known for pandemics is influenza virus A (Kapoor and Dhama 2014). This viral strain functions through a different charged sense located in its RNA genome; an area where deleterious mutations can increase in the body of its hosts allowing replication (Webster and Govorkova 2014). The popular subtype that cause the respiratory immune issue is mostly from H1N1; a serious and deathly disease (Kapoor and Dhama 2014). While influenza virus A can cause numerous complications to the human population it is also known for its relationship among humans and mammals (Kapoor and Dhama 2014). The virus circulates among many bird species causing concerns and risks to spread in further populations worldwide (Webster and Govorkova 2014). NEED MORE INTRO
Avian influenza results from infection by viruses belonging to the species influenza A virus, genus influenza virus A and family Orthomyxoviridae. These viruses are also called type A influenza viruses. Influenza A viruses are further classified into subtypes based on two surface proteins, the hemagglutinin (HA) and neuraminidase (NA) (Tong et al, 2013). The viruses are roughly spherical (120 nM) with glycoprotein spikes on the surface and genome consisting of also eight RNA fragments that encode 10 proteins. The haemagglutinin (HA), neuraminidase (NA) and matrix (M2) proteins are embedded in the envelope lipid bilayer derived from the host cell (Lamb and Krug, 2001) (figure1). The M1 protein underlying the envelope is the major determinant
Swine flu viruses do not normally infect humans. However, sporadic human infections with swine influenza viruses have occurred. When this happens, these viruses are called “variant viruses.” They also can be denoted by adding the
There are three types of influenza viruses, namely A, B, and C. Of the three, type C is the least harmful and type A is the most lethal because of its ability to mutate quickly. Furthermore, type A viruses affect a variety of animals from humans, pigs, and horses, to sea mammals, and birds. Type A viruses also have a large number of smaller subtypes as well, all of which reside
To say that the flu of 1918 (The Spanish flu) was huge would be an understatement. Over the course of two years this flu killed millions of people not only in the United States but a total of five hundred million people worldwide. The flu is caused by the infectious types of the Influenza virus A, B and C. Types A and B are what cause the seasonal flu. Type A is further broken down into two classifications based on their proteins, these classifications are: hemagglutinin (HA) and neuraminidase (NA).