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Vaccination Case Studies

Decent Essays

The study was published in the Heart British Medical Journal and took place in Sydney Australia between 2008 and 2010. The study attempted to look at the relation between Influenza and whether or not it was a precipitant to acute myocardial infarction. Potential population health benefited was identified as the vaccine effectiveness rate was 45% for patients at risk for ischemic heart disease (MacIntyre, 2015). This shows that vaccination efforts could possess secondary benefits beyond the primary purpose of vaccination. Weakness in the study is that it allowed participants in with previous cardiovascular events to be able to participate in the study. Though the article further stated that it excluded participants specifically with AMI events in the last 12 months, it allowed patients with history of angina to participate (MacIntyre, 2015). The weakness that I see in this decision is that there is a possibility that individuals with angina cases were misdiagnosed as something less severe than what they actually have (MacIntyre, 2015). Limited Variation in ethnicity could also be considered a weakness in this study. Listed below is the statistical breakdown displaying percentages of total participants for cases as well as for controls. …show more content…

Of those three researchers, one was also funded by Merck and Pfizer while also funded by GSK, CSL, and Sanofi Pasteur (MacIntyre, 2015). There is always the possibility that when individual researchers in a study are being funded by entities that gain more from successful results could cause pressure on authors of the study into manipulating end results. There is also a risk in future funding for these researchers if favorable results in these studies are not reported. Favorable results can increase sale of vaccine that is linked to also reducing rate of

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