1) Time-of-flight: Suppose that you have a time-of-flight mass spectrometer with a detector that can clearly resolve ion signs that are at least 14.0 nanoseconds apart in arrival time. Given a flight tube length of 1.40 m total field-free distance from source to detector, and a source with a potential that extends over 3.0 cm (i.e., d = 3 cm), a) determine the minimum source voltage required to ensure that two proteins with masses 2273.5 amu and 2271.8 amu are adequately resolved. Assume that all ions gain the full source energy possible, and that there is no temporal spread in the ion signal.

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1) Time-of-flight: Suppose that you have a time-of-flight mass spectrometer with a
detector that can clearly resolve ion signs that are at least 14.0 nanoseconds apart in
arrival time. Given a flight tube length of 1.40 m total field-free distance from source to
detector, and a source with a potential that extends over 3.0 cm (i.e., d = 3 cm),
a) determine the minimum source voltage required to ensure that two proteins with
masses 2273.5 amu and 2271.8 amu are adequately resolved. Assume that all ions gain
the full source energy possible, and that there is no temporal spread in the ion signal.
Transcribed Image Text:1) Time-of-flight: Suppose that you have a time-of-flight mass spectrometer with a detector that can clearly resolve ion signs that are at least 14.0 nanoseconds apart in arrival time. Given a flight tube length of 1.40 m total field-free distance from source to detector, and a source with a potential that extends over 3.0 cm (i.e., d = 3 cm), a) determine the minimum source voltage required to ensure that two proteins with masses 2273.5 amu and 2271.8 amu are adequately resolved. Assume that all ions gain the full source energy possible, and that there is no temporal spread in the ion signal.
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