1. A drug given intravenously result in an AUC 60ug/ml-hr. if same dose of drug is given orally and the resulting auc is 300 ug/ml-hr, what percentage of the oral dose reaches the blood stream?
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Solve and show the solution pleaes, thanks.
1. A drug given intravenously result in an AUC 60ug/ml-hr. if same dose of drug is given orally and the resulting auc is 300 ug/ml-hr, what percentage of the oral dose reaches the blood stream?
2. What is the administration rate of theophylline representing 0.8of the administered dose, when aminophylline is infused at 75mg/hr?
3. Four hours following the IV administration of a drug, a patient 70kg was found too have a plasma concentration of 5.6mcg/ml. Assuming the Vd is 10% of body weight, what is the amount of drug in mg, present in body fluids?
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- Using conversion factors, solve each of the following clinical problems:a. The physician has ordered 1.0 g of tetracycline to be given every six hours to a patient. If your stock on hand is 500-mg tablets, how many will you need for one day’s treatment?b. An intramuscular medication is given at 5.00 mg / kg of body weight. What is the dose for a 180-lb patient?c. A physician has ordered 0.50 mg of atropine, intramuscularly. If atropine were available as 0.10 mg /mL of solution, how many milliliters would you need to give?d. During surgery, a patient receives 5.0 pt of plasma. How many milliliters of plasma were given?Recall the power law equation Y = aXb. Which of the following statements is true? : a) a = 0.34 and b = 1 best describes homeotherms; a = 0.13 and b = 0.75 best describes poikilotherms b) a = 0.34 and b = 0.75 best describes poikilotherms; a = 0.13 and b = 0.75 best describes homeotherms c) a = 0.34 and b = 0.75 best describes homeotherms; a = 0.13 and b = 1 best describes poikilotherms d) a = 0.34 and b = 0.75 best describes homeotherms; a = 0.13 and b = 0.75 best describes poikilothermsDrug Calculations. Solve all the questions
- Using conversion factors, solve each of the following clinicalproblems:a. A nurse practitioner prepares an injection of promethazine,an antihistamine used to treat allergic rhinitis. If thestock bottle is labeled 25 mg /mL and the order is a doseof 12.5 mg, how many milliliters will the nurse draw up inthe syringe?b. You are to give ampicillin 25 mg/kg to a child with a massof 62 lb. If stock on hand is 250 mg /capsule, how manycapsules should be given?1. What physicochemical features facilitate (1) glomerular filtration, (2) drug secrecy, and (3) drug absorption in the kidney?SOMOGYI-NELSON Method(clinical chemistry) a. What is the type of blood sample used and how much of it is added to distilled water? b. How much distilled water was used in the procedure? c. What are the protein precipitants used and indicate the specific concentration of each? d. What is the color of the precipitate?