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15. Write short note on the given topics:
1. Bioavailability of drug
please answer at your own words
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- 10. Write short note on the given topics: 1. Bioavailability of drug please answer at your own words4. Please include any three adverse drug-related hemolysis consequences.4) Which of the following is a major cause of prescribing errors? A) Lack of training for the prescriber B) Lack of drug availability C) Misunderstanding the symptoms given by the patient D) Illegible handwriting
- 1.Chemotherapy's definition 2.Broad vs. narrow spectrum: applications 3.Explain why superinfections are important. 4.Explain the relevance of positive and negative medication interactions. 5 5.Antibacterial and anti-eukaryotic (fungus, protozoa, helminths) medication limitations15- Which of the followings is TRUE regarding "Therapeutic index" a.The value of therapeutic index can indicate the pharmacokinetics of the drug b.It is the ratio of effective dose/ toxic dose c.Drugs with low value of therapeutic index is a safe drug d.Low value of "therapeutic index" means that we need to monitor the patient carefully2) What is a safe dose of IV Cefazolin for a pediatric patient.
- 1. Explain the importance of solubility in drug product formulation. 2.Case Study Hibiscus Medical Centre has been in operations for over eighteen (18) years. They specialize in Plastic and Restorative Surgery. One of their physicians has recently found himself in a lawsuit for $850 000. In administering a standard diagnostic procedure, which involved injecting the patient with a certain drug, to conduct an abdominoplasty procedure, she became paralyzed. The physician in his twenty (20) years of practice and twelve (12) years at the Centre has performed this standard procedure without any adverse effects. However, the lawyer of the Centre and the physician has notified them that more than likely the plaintiff’s legal team will utilize the res ipsa loquitur doctrine which will permit the jury to lean favorably toward the plaintiff unless the physician can prove that he was without a doubt not negligent. Questions Justify what defense the physician and his Centre’s legal team can employ against this negligence claim.5. A physician orders Vistaril 50 mg IM stat for a patient with pruritus (itching). The patient weighs 132 pounds. A. What is the recommended dosage range in mg for this patient? B. Is the dose safe as ordered? C. How many mL of Vistaril should be injected? D. What is the maximum recommended mg per day?
- *1.5 mg po t.i.d. How many 0.5 mg tablets of this antianxiety drug will you administer to the patient who suffers from panic attacks? *Madonna weighs 52 kg and is 160 cm in height. Estimate her BSA. * The dosage range for the antineoplastic agent Mithracin (plicamycin) is 25–30 mcg/kg daily. What is the safe dosage range in mg per day for a patient who weighs 190 pounds and has a malignant tumor?6. Write the detailed note on routes of drug administration.1. Provide a rationale for combination drug therapy, using an anti-HIV model 2. Relate side effects and toxicity of anti protozoan drugs to their mechanism of action.