2. The TP53 gene normally functions as a tumor suppressor by preventing abnormal cell growth but is commonly found mutated in cancer cells, resulting in uncontrolled cell growth. You plan to use genetic tools to remove mutated TP53 from plasma cells. Answer the following questions. B) Is ex vivo or in vivo gene therapy/editing most appropriate? Explain why.

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter16: Regulation Of Gene Expression
Section: Chapter Questions
Problem 9TYK
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2. The TP53 gene normally functions as a tumor suppressor by preventing abnormal cell growth but is
commonly found mutated in cancer cells, resulting in uncontrolled cell growth. You plan to use genetic
tools to remove mutated TP53 from plasma cells. Answer the following questions.
B) Is ex vivo or in vivo gene therapy/editing most appropriate? Explain why.
Transcribed Image Text:2. The TP53 gene normally functions as a tumor suppressor by preventing abnormal cell growth but is commonly found mutated in cancer cells, resulting in uncontrolled cell growth. You plan to use genetic tools to remove mutated TP53 from plasma cells. Answer the following questions. B) Is ex vivo or in vivo gene therapy/editing most appropriate? Explain why.
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