4. Cancer cells keep proliferation and eventually kills the host (human body). Unfortunately, you are diagnosed to have a small tumor (aggregation of cancer cells) of 1 mm in diameter (or 1 million cells). How big will the tumor 88 O be if it were untreated for two months (60 days)? Assume your cancer cells divide every 6 days. A. 10 million cells, B. 1 billion cells, C. 40 trillion cells. D. 1 million cells.
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- With regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal, which means they are derived from asingle mutant cell.B. To become cancerous, cells usually accumulate multiplegenetic changes that eventually result in uncontrolledgrowth.C. Most cancers are caused by oncogenic viruses.D. Cancer cells have lost the ability to properly regulate celldivision.Which of the following statements are correct about tumors and metastasis (select all that apply)? A. The majority of cancer deaths are due to primary tumor B. Loss of basement membrane by tumor mass is strong predictor of metastasis potential C. The tissue stroma contributes to whether a tumor cell will metastasize D. The majority of life threatening tumors occur in epithelial tissues E. The tendency of a primary tumor to metastasize is similar across different tissue typesWhich of the following are characteristics of benign tumors? Select all that apply. a.They can migrate and grow in other tissues through metastasis. b.They grow quickly. c.They are slow growing. d.They stay in their home tissue.
- Which of the following statements are correct about tumor cell masses (select all that apply)? A. Stromal cells of tumor masses are generally just contaminants and play no role in tumor progression B. Most stromal cells are of mesenchymal origin C. Fibroblasts, macrophages and lymphocytes are commonly found in the stroma of tumor masses D. In Hodgkin's Lymphoma, the majority of cells in the tumor mass are neoplastic E. In carcinomas, neoplastic and stromal cells are present at similar numbersThe majority of metastases are the result of cancer cell invasion through which one of the following (select one)? A. Soft tissues B. Skin C. Blood Vessels D. Lymphatic vessels E. BoneWhen cancer cells metastasize, they: a. b. ○ c. travel to distant and different body parts to begin new tumors. stay in their place of origin to destroy adjacent tissues. are not able to invade blood vessels.
- Which of the following factors contributes to angiogenesis as a result of a tumor growth? Select all that apply: a. Increasing tumor's access to oxygen and nutrients b. Increasing tumor's ability for growth, invasion, and metastasis c. Increasing expression of proto-oncogenes for cancer cells d. Increasing expression of tumor-suppressor genes for cancer cellsWhich of the following cell-types are most likely to secrete Matrix Metalloproteases (MMPs) that remodel ECM near tumor (select all that apply)? A. Carcinoma Cells B. Mast cells C. Normal Epithelial Cells D. Macrophages E. FibroblastsWhich of the following is typical of cancer cells? A. The parent cell of the tumor contains a single mutation in a single checkpoint gene. B. Malignant cells migrate. C. Cancer cells lose the ability to divide. D. Products of oncogenes inhibit mitosis E. Benign tumors invade normal tissue.
- Which of the following is NOT an example of fail-safe mechanisms that prevent the irregular cell divisions characteristic of cancer? a.Shortening of telomeres b.Cell division limit c.Mutation in a tumor suppressor gene d.Triggered cell deathSome types of cancers are treated with surgery, chemotherapy, stem cell replacement or radiation, similar to ultraviolet light. Why might it be beneficial to irradiate cancer cells? Choose the Best answer. A. it kills off all the cancer cells. B. it forces all cancer cells into G0 C. it will halt cell division and possibly be forced into apoptosis D. it could kill off the cancer cells, halt cell division or possibly force the cell into apoptosisge Which of the following would most likely promote necrosis? Select one: a. activation of p53 b. pathogenic infection c. cyclin d. activation of cdk e. inactivation of p53 Cycle HW due Jump to... 46 Next page cancer stem cells