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5. Define asthma, write the pharmacology of anti-asthamatics.
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- 4. Explain the role of toxicological parameters LOAEL in ensuring the safety of a drug candidate. explain at your own words?1. Explain the importance of solubility in drug product formulation. 2.Name the commonly used anticoagulants for hematological studies. Give theirmechanism of action, specific uses, advantages and disadvantages.
- 3. Why is it important for nurses to know both generic and trade names of drugs?1. What is the importance of the conduct of HTAC Framework Review for Covid-19 Vaccines Under Emergency Use Authorization? 2. Why is it important to use the HTAC recommendation framework with the FDA directive towards thevaccine process?3. What is an important counseling point when starting a patient on cinacalcet therapy?
- Explain the benefit of narrow spectrum over broadspectrum drugs6. Write the detailed note on routes of drug administration.1) A patient with heart failure, hypertension and hyperlipidemia is taking furosemide, captopril, atenolol, and simvastatin. During a scheduled physical examination, about a month after starting all the drugs, the patient reports a severe, hacking and relentless cough. Which of the following is the most likely cause of the cough? An expected effect of the captopril An allergic reaction to the statin Dyspnea due to captopril’s bronchoconstrictor action Hyperkalemia caused by an interaction between furosemide and captopril Excessive doses of furosemide, which lead to hypovolemia 2) Flecainide and propafenone are in Vaughan-Williams (antiarrhythmic) Class IC. What is the clinically relevant “take home” message about this class of drugs? Are only given for arrhythmias during acute myocardial infarction (MI) Are particularly suited for patients with low ejection fraction or cardiac output Are preferred drugs for relatively non-severe ventricular arrhythmias Have a significant…
