Help me . 2.Time(h)O2460681224A patient was given a 50 mg IV bolus dose of a drug and periodic urine sampleswere collected. The observations are as follows:UrinevolumeCollected(ml)12018089340178950Urine Time Mid-PointConc interval of TimeInterval(h)(µg/ml)(h)133506310182AmtExcretedin TimeInteval(mg)Excretion CumulativeRate(mg/h)AmountExcreted(mg)(a) Using "excretion rate" method and "amount to be excreted" method, estimate k,ku, and fe of the drug.AmountRemainingto beExcreted(mg)

In this case study, a patient received a 50 mg intravenous (IV) bolus medication dosage. Urine…

Answered: (a) Using "excretion rate" method and…

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Nursing

(a) Using "excretion rate" method and "amount to be excreted" method, estimate k, ku, and fe of the drug.

Comprehensive Medical Assisting: Administrative and Clinical Competencies (MindTap Course List)

6th Edition

ISBN:9781305964792

Author:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy Correa

Publisher:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy Correa

Chapter41: Urinalysis

Section: Chapter Questions

Problem 7CR

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Question

Help me .

2.
Time
(h)
O246
0
6
8
12
24
A patient was given a 50 mg IV bolus dose of a drug and periodic urine samples
were collected. The observations are as follows:
Urine
volume
Collected
(ml)
120
180
89
340
178
950
Urine Time Mid-Point
Conc interval of Time
Interval
(h)
(µg/ml)
(h)
133
50
63
10
18
2
Amt
Excreted
in Time
Inteval
(mg)
Excretion Cumulative
Rate
(mg/h)
Amount
Excreted
(mg)
(a) Using "excretion rate" method and "amount to be excreted" method, estimate k,
ku, and fe of the drug.
Amount
Remaining
to be
Excreted
(mg)

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