A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: HỌ-P-NH -0- OH OH OH OH OH ΝΗ NH₂ Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose that this compound was introduced into a cell in place of the GTP normally present. What would happen to the G-protein signaling system? What would occur to the response activities governed by this system? C. In another case, you have a cell in which the ß subunit of the G-protein complex has been mutated such that it can no longer change to the active state. What will happen to signal transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section4.5: Intercellular Communication And Signal Transduction
Problem 3CYU: Outline the three general means by which binding of a water soluble extracellular chemical messenger...
icon
Related questions
Topic Video
Question

please please do it urgently

its urgent

(C)
activated
a subunit
activated G-protein subunits
GTP
Figure 16-17 Essential Cell Biology. 2. (2004 Garland Science)
HO-P-NH- -0
activated
By complex
A. Which of the events involved in this signaling system would be termed signal
transduction? Please briefly explain your answer.
B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP:
OH OH OH
OH OH
ΝΗ
Edit View Insert Format Tools Table
NH₂
Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose
that this compound was introduced into a cell in place of the GTP normally present. What would
happen to the G-protein signaling system? What would occur to the response activities
governed by this system?
C. In another case, you have a cell in which the ß subunit of the G-protein complex has been
mutated such that it can no longer change to the active state. What will happen to signal
transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.
Transcribed Image Text:(C) activated a subunit activated G-protein subunits GTP Figure 16-17 Essential Cell Biology. 2. (2004 Garland Science) HO-P-NH- -0 activated By complex A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: OH OH OH OH OH ΝΗ Edit View Insert Format Tools Table NH₂ Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose that this compound was introduced into a cell in place of the GTP normally present. What would happen to the G-protein signaling system? What would occur to the response activities governed by this system? C. In another case, you have a cell in which the ß subunit of the G-protein complex has been mutated such that it can no longer change to the active state. What will happen to signal transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.
Certain extracellular signal molecules can bind to their specific transmembrane receptor protein and, as a
result, activate a G-protein complex. This signaling system is diagramed in the following figure:
receptor protein
(A)
signal
molecule
(B)
(C)
GDP
GTP
activated
a subunit
inactive G protein
a
B
O
H
GOP
O
HỌ-P-NH-P-0
OH
Figure 16-17 Essential Cell Biology, 2/e. (©2004 Garland Science)
EXTRACELLULAR SPACE
OH OH
plasma
membrane
activated G-protein subunits
activated
By complex
A. Which of the events involved in this signaling system would be termed signal
transduction? Please briefly explain your answer.
CYTOSOL
B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP:
ΝΗ
N NH₂
Transcribed Image Text:Certain extracellular signal molecules can bind to their specific transmembrane receptor protein and, as a result, activate a G-protein complex. This signaling system is diagramed in the following figure: receptor protein (A) signal molecule (B) (C) GDP GTP activated a subunit inactive G protein a B O H GOP O HỌ-P-NH-P-0 OH Figure 16-17 Essential Cell Biology, 2/e. (©2004 Garland Science) EXTRACELLULAR SPACE OH OH plasma membrane activated G-protein subunits activated By complex A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. CYTOSOL B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: ΝΗ N NH₂
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Gene expression
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap …
Human Physiology: From Cells to Systems (MindTap …
Biology
ISBN:
9781285866932
Author:
Lauralee Sherwood
Publisher:
Cengage Learning