Actin filaments, microtubules, and bacterial flagella are all built from small subunits. Describe three advantages of assembling long filamentous structures from subunits rather than from single, long proteins.
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Actin filaments, microtubules, and bacterial flagella are all built from small subunits. Describe three advantages of assembling long filamentous structures from subunits rather than from single, long proteins.
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- Microfilaments are long filamentous proteins made up of many globular proteins. What main protein are microfilaments composed of?The concentration of actin in cells is 50–100 timesgreater than the critical concentration observed for pureactin in a test tube. How is this possible? What prevents theactin subunits in cells from polymerizing into filaments?Why is it advantageous to the cell to maintain such a largepool of actin subunits?Identify the structural makeup of actin filaments, intermediatefilaments, and microtubules
- Explain how the structure of intermediate filaments makes them better suited to provide mechanical strength than either microtubules or actin filaments.?Which of the following describes an F-actin microfilament? A flexible, helical filament composed of two strands assembled from G-actin 13 protofilaments composed of heterodimers with a hollow core a flexible filament composed of 13 interwoven protofilaments Eight tetramers twisted into a rope-like filamentNeurofilament proteins assemble into long, intermediate filaments , found in abundance running along the length of nerve cell axons. The C-terminal region of these proteins is an unstructured polypeptide, hundreds of amino acids long and heavily modified by the addition of phosphate groups. The term “polymer brush” has been applied to this part of the neurofilament. can you suggest why?
- If GTP hydrolysis occurs on a tubulin molecule at the plus end of a microtubule filament before another tubulin molecule is added, what typically happens to the microtubule? answer and explainWhat keeps the actin monomers from polymerizing totally into filaments? explain.Actin filaments have a defined polarity. What is filament polarity? How is it generated at the subunit level?
- Actin and microtubules have polarity, intermediate filaments have no polarity. What is the main consequence of this difference?a) Are actin filaments subject to the same "dynamic instability" as microtubules? Yes or no? b)Explain how both actin and microtubules polymerize and depolymerize.Describe the mechanisms by which microfilaments assemble.