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- A gene that codes for a positive cell cycle regulator is called a(n) _______. a. kinase inhibitor b. tumor suppressor gene c. proto-oncogene d. oncogeneCancer causing genes are called ________. a. transformation genes b. tumor suppressor genes c. oncogenes d. mutated genesMost forms of cancer involvea. the activation of a single oncogene.b. the inactivation of a single tumor-suppressor gene.c. the activation of multiple oncogenes.d. the activation of multiple oncogenes and the inactivation ofmultiple tumor-suppressor genes.
- Mutations to proto-oncogenes act toa. increase cell division. c. repress oncogenes.b. increase DNA repair. d. decrease cell division________ are changes to the nucleotides in a segment of DNA that codes for a protein.a. Proto-oncogenesb. Tumor suppressor genesc. Gene mutationsd. Negative regulatorsNormal (nonmutant) tumor-suppressor genes often functiona. as negative regulators of cell division.b. in the maintenance of genome integrity.c. in the stimulation of cell division.d. as both a and b.
- A tumor suppressor genea. inhibits cell division.b. opposes oncogenes.c. prevents cancer.d. is subject to mutations.e. All of these are correct.Describe, using specific examples, the differences in how a growth factor gene and a tumor suppressor gene can become oncogenes.Which of the following statements correctly describes a characteristic of tumor-suppressor gene? a) they are frequently overexpressed in cancerous cells. b) they are cancer-causing genes introduced into cells by viruses. c) they encode proteins that help prevent uncontrolled cell growth. d) they often encode proteins that stimulate the cell cycle.
- In a wild-type cell, the function of a protein encoded by a tumor-suppressor gene is to cause a cell to ______. A.) stop dividing B.)extend its telomeres C.) grow toward a new blood vessel D.) respond to a growth factorA gene that codes for a positive cell-cycle regulator is called a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.Which of the following is not a tumor suppressor gene? a.RET b.RB c.BRCA1 d.BRCA2
