Are the following events best explained by mutation or epimutation? A. imprinting of the Igf2 geneB. variation in coat color in mice carrying the Avy alleleC. formation of cancer cellsD. variation in flower color between different strains of pea plants,such as purple versus whiteE. X-chromosome inactivation
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Are the following events best explained by mutation or epimutation?
A. imprinting of the Igf2 gene
B. variation in coat color in mice carrying the Avy allele
C. formation of cancer cells
D. variation in flower color between different strains of pea plants,
such as purple versus white
E. X-chromosome inactivation
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Solved in 2 steps
- In fruit flies, dosage compensation is achieved bya. X-chromosome inactivation.b. doubling the expression of genes on the single X chromosome in the male.c. decreasing the expression of genes on the two X chromosomes by 50% in the female.d. all of the above.Red–green color blindness in humans is due to an X-linked recessive gene. A woman whose father is color blind possesses one eye with normal color vision and one eye with color blindness. a. Propose an explanation for this woman’s vision pattern. Assume that no new mutations have spontaneously arisen. b. Would it be possible for a man to have one eye with normal color vision and one eye with color blindness?Red–green color blindness in humans is due to an X-linked recessive gene. A woman whose father is color blind possesses one eye with normal color vision and one eye with color blindness. Q. Propose an explanation for this woman’s vision pattern. Assume that no new mutations have spontaneously arisen.
- A recessive mutation pd causes purple eyes in Drosophila, in contrast to the wildtype red eyes. A dominant suppressor called Su can restore the color of pd/pd fly eyes to red. If you cross a pd/+ ; Su/+ fly to a pd/pd ; +/+ fly, what proportion of the offspring will have purple eyes?Which of the following is a possible explanation for pleiotropy?a. The expression of a single gene can affect cell function in morethan one way.b. A gene may be expressed in different cell types in a multicellularorganism.c. A gene may be expressed at different stages of development.d. All of the above are possible explanations.Chiasmatic interference is caused by: A. An artifact caused by the Chi square distribution. B. Genes physically being distant but on the same chromosome. C. Some genes are naturally more charismatic than others. D. Epistasis combined with suppression. E. The size of the synaptonemal complex
- Almost all calico cats (one is pictured in FIGURE 10.7B) are female. Why? B When this calico cat was an embryo, one of the two X chromosomes was inactivated in each of her cells. The descendants of the cells formed her adult body, which is a mosaic for expression of X chromosome genes. Black fur arises in patches where genes on the X chromosome inherited from one parent are expressed; orange fur arises in patches where genes on the X chromosome inherited from the other parent are expressed. FIGURE 10.7 Animated X chromosome inactivation..Certain forms of human color blindness are inherited as X-linkedrecessive traits. Hemizygous males are color-blind, but heterozygous females are not. However, heterozygous females sometimeshave partial color blindness.A. Discuss why heterozygous females may have partial color blindness.B. Doctors identified an unusual case in which a heterozygousfemale was color-blind in her right eye but had normal colorvision in her left eye. Explain how this might have occurred.Which of the following statements is FALSE? Inactivation of one of the two X chromosomes in the somatic cells of mammalian females..... a. underlies the Calico phenotype in cats. b. leads to cellular mosaicism in females heterozygous for an X-linked gene. c. affects 75 % of the paternal and 25 % of the maternal X-chromosomes of a mammalian body. d. leads to the formation of a Barr body in female cells' nuclei. e. is the mechanism in mammals to compensate for the higher dosage of X-linked genes in females as compared to males.
- Which of the following statements is false? Dosage compensation is accomplished in humans by stimulation of gene expression from the single X chromosome. Dosage compensation is accomplished in humans by inactivating a female X chomosome. An individual with Turner Syndrome has no Barr bodies. An individual with Klinefelter syndrome generally has one Barr body. A typical XX human female has one Barr body.In Drosophila, a female fly is heterozygous for three mutations, Bareyes (B), miniature wings (m), and ebony body (e). Note that Bar isa dominant mutation. The fly is crossed to a male with normal eyes,miniature wings, and ebony body. The results of the cross are asfollows.111 miniature29 wild type117 Bar26 Bar, mimatue101 Bar, ebony31 Bar, miniature, ebony35 ebony115 miniature, ebonyInterpret the results of this cross. If you conclude that linkage isinvolved between any of the genes, determine that map distance(sbetween them.In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9 No other phenotypes were observed.(a) What progeny phenotypes are missing? Why?