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- QUESTION: A 35-year-old man is known to have been HIV-positive for the past 10 years. Physical examination now shows multiple reddish purple, nodular skin lesions with the microscopic appearance shown in the figure. These lesions have been slowly increasing for the past year. Which of the following risk factors is most likely to play a role in the development of these skin lesions? A Antiretroviral therapy B Epstein-Barr virus infection C Hyperlipidemia D Mycobacterium avium complex infection E Sexual intercourse do fast pleasecomprehension) A scientist hypothesized that her vaccine would stimulate the immune system to attack melanoma (skin cancer) tumors and reduce their growth. To test the hypothesis, 100 melanoma patients were injected with the vaccine in a saline solution (Group A) and 100 melanoma patients were injected with only the saline solutionquestion: Can you summarize and explain for me what you want to tell in the article below? When I read it myself, I do not understand exactly what is meant by the article. It would be nice if you could highlight the important points. You can use them in a figure or diagram to explain. thank you and hava a nice day :) Article: Nanomaterial-Based Vaccine Development and Immunomodulation Following the publication of the genetic sequence of SARS-CoV-2 on January 11, 2020, intense research efforts have been devoted to developing a vaccine against COVID-19. With unprecedented speed, this extraordinary scientific mobilization led the first vaccine candidate to enter the Phase I human clinical trial on March 16, 2020, and other novel candidates are rapidly following. Up to May 22, 2020, there are 10 COVID-19 candidate vaccines in clinical evaluations and 114 in preclinical development. Concerning vaccine and immunization research, nanomaterials can assist in multiple ways to boost the…
- question: Can you summarize and explain for me what you want to tell in the article below? When I read it myself, I do not understand exactly what is meant by the article. It would be nice if you could highlight the important points. You can use them in a figure or diagram to explain. thank you and hava a nice day :) Article: Can Nanotechnology Help to Control the Cytokine Storm? One of the main features of COVID-19 is the triggering of a cytokine storm in the body, also known as cytokine release syndrome (CRS), which results from an excessive immune response and leads to the severe deterioration of patient health. This inflammatory storm is one of the major causes of the acute respiratory distress syndrome (ARDS) that is often associated with multiple-organ failure, representing the leading causes of death in critical patients. In particular, the role of interleukin (IL)-6 has been highlighted in patients requiring assisted ventilation. Ongoing clinical trials are testing drugs that…macrophages Question 48 Please describe/name the structural variants describe in the picture: Courtesy of CRC Press/Taylor & Francis Group А. 1 ACGCTGCGGTTCGATAGT 2 ACGCTGCG-TTCGATAGT В. 1 ACGCTGCGGTT-CGATAGT ACGCTGCGGTTTCGATAGT C. 1 ACGCTGCGGTTCGATAGT ACGCTGC CA GATAGT D. 1 CACACACACACACACACACACACA 2 CACACACACACACACACACACA E. 1 100 100 | 100 100 2 100 100 100liges 3. Tyrosine kinase receptors are pairs of proteins that span the plasma membrane. On the extracellular side of the membrane, one or more sites are present that bind to signaling ligands such as insulin or growth factors. On the intracellular side, the enas of peptide chains on each protein phosphorylate the other member of the pair, providing active docking sites that initiate cellular responses. The signal is switched off by dissociation of the ligand. For each ligand-receptor system, the equilibrium constant, k, controls the distribution of receptor-bound and unbound ligands. In systems with large values of k, a site is likely to be occupied, even at low concentrations of ligand. When k is small, the likelihood of binding is low, even when the concentration of ligand is high. To initiate a new stimulus response cycle for the receptor, the ligand must dissociate. Larger values of k mean that the receptor is more likely to be occupied and thus unavailable to bind another ligand.…
- PROTEINS1. What will happen to free tyrosine after being subjected to xanthoproteic analysis (is it positive or negative, include color)2. What will happen to lysine after being subjected to millon's analysis (is it positive or negative, include color)CASE STUDY Cancer-killing bacteria Ralph, a 57-year-old man, was diagnosed with colon cancer.His oncologist discussed the use of radiation andchemotherapy as treatments, both of which can causedebilitating side effects. Ralph decided to explore other optionsand went to a cancer clinic. He learned that researchers in asynthetic biology program were testing the use of geneticallymodified bacterial cells designed to selectively invade specifictumors and kill cancer cells, with no effects on normal cells.Ralph decided to participate and was informed that he wouldbe part of a phase III trial, comparing the effects of the modifiedbacterial cell treatment against conventional chemotherapy.However, as part of the trial, he would be randomly assigned toreceive one or the other treatment. He was disappointed to learnthis, because he assumed that he would receive the bacterialtherapy.Question: Informed consent is legally and ethically required beforesomeone participates in a clinical trial.…THE MOLECULAR GENETICS OF CYSTIC FIBROSIS 2. What is the sequence of bases on the strand of DNA that is complementary to the template strand? 3. What mRNA will be formed from the template strand of DNA? The following is the base sequence of DNA that codes for amino acids 506-510 of the protein that regulates the chlorine channels in the cell membrane. This protein contains a total of 1476 amino acids so this is a small part of the entire gene. DNA Template Strand: TAGTAGAAACCACAA 1. What is the minimum number of DNA nucleotides in this whole gene? 4. What amino acids will this mRNA code for? 5. If the 6th, 7th and 8th bases in the template strand of the DNA are removed, rewrite the new template strand below. 1 6. When the template strand of the DNA is changed, this is referred to as a mutation. What kind of mutation is this? 7. What mRNA will be formed from the mutated template strand of DNA? 8. What amino acids will this new mRNA from the mutated template strand code for? 9. Are these…
- question: Can you summarize and explain for me what you want to tell in the article below? Can you explain the figure? When I read it myself, I do not understand exactly what is meant by the article. It would be nice if you could highlight the important points. You can use them in a figure or diagram to explain. thank you and hava a nice day :) Article: Nanotechnology Tools to Detect SARS-CoV-2 Standard procedures for detecting the virus from nasopharyngeal and/or oropharyngeal swabs have been reviewed recently and are primarily based on reverse transcription polymerase chain reaction (RT-PCR). Here, we would like to mention some preliminary ideas on nanotechnology-based assays to monitor the presence of SARS-CoV-2. A simplified test and variants thereof to detect viral proteins (e.g., HIV or influenza virus) without the need for expensive equipment is based on the color change of Au NPs bound to antibodies. Similar to the enzyme-linked immunosorbent assay (ELISA) antibodies coupled…Can you please help me with question( 9) 5. In the film, Dr. Jablonski explains that melanin, located in the top layer of human skin, absorbs UV radiation, protecting cells from the damaging effects of UV. Genetics determines the type of melanin (i.e., brown/black eumelanin or red/brown pheomelanin) and the amount of melanin present in an individual’s cells. Based on this information, write a hypothesis for where in the world you would expect to find human populations with darker or lighter skin pigmentation (i.e., different amounts of melanin). 9. Do these data support your hypothesis from Question 5? Justify your answer.Remember for T/F questions, either answer TRUE or FALSE, but if the answer is FALSE make sure to explain WHY the answer is false. Proteins that were made to be sorted OUT of the endoplasmid reticulum (ER) do NOT have a retention signal so that the protein can leave the ER.