Critically discuss the following statement: ‘The success of PARP inhibitor therapy in ovarian cancer has led to the development of novel synthetic lethal strategies targeting DNA damage response in solid tumours’. Include challenges of PARP inhibition therapy as well as future developments in your answer.

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Chapter22: Diet And Cancer
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Critically discuss the following statement: ‘The success of PARP inhibitor therapy in ovarian cancer has led to the development of novel synthetic lethal strategies targeting DNA damage response in solid tumours’. Include challenges of PARP inhibition therapy as well as future developments in your answer.

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PARP/BRCIA combination works in detail and then progress to more hovel developments

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can you go more in depth  on molecular and cellular aspects of cancer and current approaches in cancer diagnosis and treatment.

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