Kindly explain the chart Cell Membrane PhospholipidsPhospholipase A,Arachidonic Acid5-lipoхуgenaseCOX-1 or COX-25-HPETECyclic endoperoxidesLEUKOTRIENESPGI,Vasodilator, hyperalgesic,inhibits plateletaggregationТХА,stimulates plateletaggregation,vasoconstrictorPGF,PGD,inhibits plateletaggregationPGE,broncoconstrictorvasodilator

Prostaglandins are different compounds derived from lipids. The prostaglandins perform different…

Answered: Cell Membrane Phospholipids…

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter21: Heparin Infusion Calculations

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Problem 4SST

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op of Form Normal Levels of Substances in the Arterial Blood: pH 7.40 + 0.05 pCO2 (partial pressure of carbon dioxide) 40 mm Hg pO2 (partial pressure of oxygen) 90 - 100 mm Hg Hemoglobin - O2 saturation 94 - 100 % [HCO3-] 24 meq / liter Vignette #1: A 21-year-old noncompliant female with a history of type I (insulin-dependent) diabetes mellitus was found in a coma. Her blood glucose was high, as well as her urine glucose, urine ketones, and serum ketones. Her serum bicarbonate was < 12 mEq/L. Her respiration was exaggerated, and her breath had an acetone odor. Her blood pressure was 90/60 and his pulse weak and rapid (120). 1. Define noncompliant. 2. Is this person experiencing ketoacidosis or insulin shock? Explain your answer. 3. Why is the serum bicarbonate low? 4. What is the acid-base status of this individual? 5. What are the causes of the dyspnea, hypotension, and tachycardia? 6. What type of treatment does this person need?…
a 54 year old man develops vomiting and diarrhea over a 24 hour period. his serum sodium concentration is 140 mEq/L. Intravenous infusion of isotonic saline is initiated . which of the following changes and intracellular and extracellular fluid volume is most likely to result from this infusion a ICF volume : decreased , ECF decreased b. ICF volume :increased , ECF decreased c. ICF volume : increased , ECF. increased d. ICF volume : increased , ECF. no change e. ICF volume : no change , ECF increased
It is known that heparin acts by increasing the activity of antithrombin, causing a conformational change. LMWHs inhibit mainly factor Xa. Although low doses of heparin act primarily by neutralizing factor Xa, at high doses it prevents thrombin-induced platelet activation and prolongs bleeding time. What are major clinical benefits using heparin or LMWHs?
Normal Levels of Substances in the Arterial Blood: pH 7.40 + 0.05 pCO2 (partial pressure of carbon dioxide) 40 mm Hg pO2 (partial pressure of oxygen) 90 - 100 mm Hg Hemoglobin - O2 saturation 94 - 100 % [HCO3-] 24 meq / liter Vignette #1: A 21-year-old noncompliant female with a history of type I (insulin-dependent) diabetes mellitus was found in a coma. Her blood glucose was high, as well as her urine glucose, urine ketones, and serum ketones. Her serum bicarbonate was < 12 mEq/L. Her respiration was exaggerated, and her breath had an acetone odor. Her blood pressure was 90/60 and his pulse weak and rapid (120). 4. What is the acid-base status of this individual? 5. What are the causes of the dyspnea, hypotension, and tachycardia? 6. What type of treatment does this person need?
Pernicious most common in older pe people Which choices list the correct relationships among the factors that cause this disorder? -The reduced synthesis Vitamin B 12 results in the production many platelets. -The reduced af intrinsic factor means that vitamin cannot be absorbed, and many red blood cells are destroyed -The reduced secretion intrinsic factot that vitamin carinot bo absorbedand macrocytes are produced instead of erythrocytes -The increased secretion of intrinsic in excess levels of Vitamin causes the synthesis of too many red blood cells for the to break down.
Diabetes describe the impact of the DDC on two different body systems. Identify the impacts systems and explain the impact. For example, sickle cell anemia impacts the cardiovascular system because the irregular shaped red blood cells makes it difficult for them to travel through the blood vessels”
Establish the relationship between kwashiorkor and edema. Briefly explain the Renin-angiotensin mechanism indicating the treatment or drug target sites of hypertensive patients in regulating blood pressure. A 63-year old man took four bottles of Kasepreko, an alcoholic beverage at a funeral ceremony and refused to eat my food. He wakes up early morning at the funeral grounds feeling very hungry but again refused to eat but rather ordered for alcohol. Hours later, after he had drunk the alcohol, he became unconscious and was rushed to the nearest hospital and later developed coma. A request by the clinician and a blood analysis by the laboratory scientist revealed low blood glucose levels. Briefly explain the mechanism behind the low blood glucose level and the development of coma by the patient. A 72-year old female diabetic patient in a state of ketoacidosis and was found to be breathing rapidly. Laboratory investigations revealed low HCO-3, low PaCO2 and high PaO2. Briefly explain…
Which of these three paracrine chemicals cause vasodilation? ATP adenosine nitric oxide
5. A patient you are monitoring has been on Telmisartan (Cozaar), an angiotensin receptor blocker for the man- agement of their hypertension. The drug must be metabolized by CYP2C9 or CYP3A4 from a 5-methanol to a 5-carboxylic acid to exhibit its effects. After 2 years of successful therapy, their blood pressure suddenly in- creases. Why might this occur and what would you sug- gest as a substitute?
Enalaprilat is a competitive inhibitor of the angiotensin-converting enzyme (ACEACE), which cleaves the blood-pressure regulating peptide angiotensin I. ACEACE has a KM=52KM=52 μMμM for angiotensin I, which is present in plasma at a concentration of 75 μMμM. When enalaprilat is present at 2.4 nMnM, the activity of ACE in plasma is 14 %% of its uninhibited activity. What is the value of KIKI for enalaprilat?
During a bout of heavy exercise, terminal resistance arterioles in a musclemay dilate and transiently increase capillary hydrostatic pressure from 30mmHg to 40 mmHg. If capillary oncotic pressure remains constant at 28mm Hg and interstitial fluid oncotic pressure remains constant at 3 mm Hg,which of the following will occur?A)Net filtration will increaseB)Net filtration will decreaseC)Only absorption will occurD)Net filtration will not changeE)Net absorption will increaseWhich of the following promotes reabsorption of water into the capillary?A)Plasma oncotic pressureB)Capillary hydrostatic pressureC)Interstitial fluid oncotic pressureD)Soluble electrolytesE)Red blood cells
Which of the following routes is used to obtain a steady-state concentration in plasma? a. Single intravenous bolus dose b. Single oral dose c. Intravenous infusion d. Single subcutaneous route

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