Complete Table 1, indicating how much (lots, little, none) of the above gene product would be made given the following mutations: • Mutation in the operator that reduces the affinity of the operator for the repressor protein (operator-constitutive mutants = Oc)? • Mutation in the promoter that reduces the affinity of the promoter for RNA polymerase (P¯)? • Mutation in the repressor gene such that the protein has lost the ability to bind allolactose (superrepressor mutant = 1s)? • Mutation in the repressor gene such that the protein has lost the ability to bind the operator (I)? Gene Status normal ос P IS 1- none (-lac) none (-lac) little lots little lots none (+lac) none (+lac) none (-lac) none (+lac) none (+lac) || none (-lac) lots lots + lactose little little little lactose none (+lac)) none (-lac) lots

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Complete Table 1, indicating how much (lots, little, none) of the above gene product would be made given the following mutations:
• Mutation in the operator that reduces the affinity of the operator for the repressor protein (operator-constitutive mutants = Oc)?
• Mutation in the promoter that reduces the affinity of the promoter for RNA polymerase (P¯)?
• Mutation in the repressor gene such that the protein has lost the ability to bind allolactose (superrepressor mutant = 1s)?
• Mutation in the repressor gene such that the protein has lost the ability to bind the operator (I)?
Gene Status
normal
ос
P
IS
1-
none (-lac)
none (-lac)
little
lots
little
lots
none (+lac)
none (+lac)
none (-lac)
none (+lac)
none (+lac)|| none (-lac)
lots
lots
+ lactose
little
little
little
lactose
none (+lac))
none (-lac)
lots
Transcribed Image Text:Complete Table 1, indicating how much (lots, little, none) of the above gene product would be made given the following mutations: • Mutation in the operator that reduces the affinity of the operator for the repressor protein (operator-constitutive mutants = Oc)? • Mutation in the promoter that reduces the affinity of the promoter for RNA polymerase (P¯)? • Mutation in the repressor gene such that the protein has lost the ability to bind allolactose (superrepressor mutant = 1s)? • Mutation in the repressor gene such that the protein has lost the ability to bind the operator (I)? Gene Status normal ос P IS 1- none (-lac) none (-lac) little lots little lots none (+lac) none (+lac) none (-lac) none (+lac) none (+lac)|| none (-lac) lots lots + lactose little little little lactose none (+lac)) none (-lac) lots
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