Consider a 1000 mL chemostat (continuous reactor) operating with cellular recycling. The bioreactor is operated at steady state with glucose limitation with F = 100 mL/h and SF = 10 g/L. The values of YX/S = 0.5 gX/gS and the kinetic constants of the microorganism under the conditions employed are known (µmax = 0.2 h-1 and KS = 1.0 g/L). Knowing that the system operates with concentration factor B = 1.5 and recycling rate R = 0.7, calculate: a) the cell concentration in the recycle stream b) the cell concentration at the output of the system (bioreactor + separator)

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
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Chapter1: Introduction
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Consider a 1000 mL chemostat (continuous reactor) operating with cellular recycling. The bioreactor is operated at steady state with glucose limitation with F = 100 mL/h and SF = 10 g/L. The values of YX/S = 0.5 gX/gS and the kinetic constants of the microorganism under the conditions employed are known (µmax = 0.2 h-1 and KS = 1.0 g/L). Knowing that the system
operates with concentration factor B = 1.5 and recycling rate R = 0.7, calculate:


a) the cell concentration in the recycle stream
b) the cell concentration at the output of the system (bioreactor + separator)

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