D) 179 (9) In an epidemiological survey for a rare disease, 1170 subjects from a city population were recruited. Based on the mouse study, a human ortholog might be a candidate gene involved in the human disease and thus was genotyped for the 1170 people. There are two alleles at a position of this gene, a major, reference allele G and a minor allele A. Among 90 people with the A allele, 50 had the disease under study and 40 were healthy. Among 1080 people with G allele, 120 had the disease while others were healthy. What is the risk ratio or relative risk for the minor allele? A) 0.1 B) 0.125 C) 10 D) 8

Biology 2e
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ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter12: Mendel's Experiments And Heredity
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D) 179
(9) In an epidemiological survey for a rare disease, 1170 subjects from a city population were
recruited. Based on the mouse study, a human ortholog might be a candidate gene involved in the
human disease and thus was genotyped for the 1170 people. There are two alleles at a position of this
gene, a major, reference allele G and a minor allele A. Among 90 people with the A allele, 50 had the
disease under study and 40 were healthy. Among 1080 people with G allele, 120 had the disease while
others were healthy. What is the risk ratio or relative risk for the minor allele?
A) 0.1
B) 0.125
C) 10
D) 8
Transcribed Image Text:D) 179 (9) In an epidemiological survey for a rare disease, 1170 subjects from a city population were recruited. Based on the mouse study, a human ortholog might be a candidate gene involved in the human disease and thus was genotyped for the 1170 people. There are two alleles at a position of this gene, a major, reference allele G and a minor allele A. Among 90 people with the A allele, 50 had the disease under study and 40 were healthy. Among 1080 people with G allele, 120 had the disease while others were healthy. What is the risk ratio or relative risk for the minor allele? A) 0.1 B) 0.125 C) 10 D) 8
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