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Q: What are cell cycle checkpoints? Why are they important
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Q: Which of the three cell cycle checkpoints represents the most important commitment for the cell to…
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Q: What is the duration of G1 checkpoint
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Describe the general conditions that must be met at each of the three main cell-cycle checkpoints.
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- Describe the purpose of cell cycle checkpoints.Which of the three cell cycle checkpoints represents the most important commitment for the cell to divide?a. Why are cell cycle checkpoints important? b. What happens to a cell that fails to meet the requirements of a checkpoint and is not able make the necessary improvements or repairs?
- Describe the three most important cell cycle checkpoints. Explain in a detailed manner and provide some sample scenarios.What cell-cycle events will be affected in a cell that produces mutated (non-functional) cohesin protein?Explain and give the importance of cell cycle checkpoints in the different phase of the cell cycle.
- If the S cyclin is mutated at its phosphorylation site, which checkpoint will be affected? Which conditions will escape from control during the cell cycle?In cell cycle, under the control system, explain in details (including roles of related proteins): During M phase, how M-Cdk can trigger cohesin dissociation as well as Mad2 triggers mitotic checkpoint to delay metaphase to anaphase transition.What factors needed to proceed with the cell cycle of G1 checkpoint?
- What are cell cycle checkpoints? Where in the cell cycle are the checkpoints found (note—incude S phase checkpoint? How do they differ? How are Rb, p53, and MPF involved in cell cycle checkpoints? What events could lead to cell cycle arrest?List and briefly describe three major cell cycle checkpoints. For each checkpoint, predict the consequences if the checkpoint fails to work properly.What are the needed materials/molecules of Mitotic checkpoint?