Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section12.6: Immune Diseases
Problem 1CYU
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Question
Describe the reasons of extensive usage of corticosteroids in the treatment of autoimmune diseases and prevention of graft rejection.
Expert Solution
Step 1
Corticosteroids are the anti inflammatory drugs which lowers the inflammation in the body. Corticosteroids are naturally produced in the body by the adrenal gland outer portion called adrenal cortex. Corticosteroids are classified into
- Glucocorticoid - It suppresses the immunity and inflammation
- Mineralocorticoid - Salt and water regulation in the body.
Synthetic corticosteroids
These are the drugs which replicate the action of naturally occurring corticosteroids. For example :
- Betamethasone
- Prednisone
- Prednisolone
- Methylprednisolone
- Dexamethasone
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