Describe why PARP inhibitors are considered targeted therapies (affecting only cancer cells and not healthy cells)? Describe their mechanism of action.
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genetics course
2. Describe why PARP inhibitors are considered targeted therapies (affecting only cancer cells and not healthy cells)? Describe their mechanism of action.
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- Need detail explanation Scenario: A 56-year-old client was diagnosed with aggressive bone cancer that required a below the knee amputation of the left leg 14 months ago. The client received recommended chemotherapy and radiation, but it was found recently that the cancer has metastasized to the chest and skull. There is lymph node involvement with a primary tumor partially obstructing the right kidney. The client was readmitted 4 days ago for removal of the remaining portion of the left leg and was told that there is no appropriate surgical or medical intervention that would be beneficial at this point in the disease process. The interdisciplinary health care team has recommended palliative care upon discharge since the client’s life expectancy is between 3 and 5 months. The client has developed a mutually respectful relationship with a nurse on the unit who has provided care throughout all previous hospitalizations. The client shares with the licensed practical nurse (LPN) that, “I…if you were to explain to a 5th grader why late stage cancer if so dangerous for your body how would you explain it ? question: explain to a 5th grader why late stage cancer if so dangerous for your body.Question- There is a difference between the cancer pathology and a predisposition to developing cancer pathology. Use your understanding of foundational concepts to distinguish between predisposition and active pathology. Then, explain why only one of the above conditions ispassed on from parent to offspring. (Be sure to identify which is passed.)
- In your own words, explain each of the hallmarks of cancer. (immortality, produce go signals, override stop signals, resist cell death, angiogenesis and how it relates to metastasis.advantages and limitations of circulating tumor dna as biomarkers for cancer detection1. "What genetic material was used in this research?" 2. How does the completion of this research advance the treatment of cancer? in typed please and this is the research "The Mystery of Metastasis"
- CASE STUDY Cancer-killing bacteria Ralph, a 57-year-old man, was diagnosed with colon cancer.His oncologist discussed the use of radiation andchemotherapy as treatments, both of which can causedebilitating side effects. Ralph decided to explore other optionsand went to a cancer clinic. He learned that researchers in asynthetic biology program were testing the use of geneticallymodified bacterial cells designed to selectively invade specifictumors and kill cancer cells, with no effects on normal cells.Ralph decided to participate and was informed that he wouldbe part of a phase III trial, comparing the effects of the modifiedbacterial cell treatment against conventional chemotherapy.However, as part of the trial, he would be randomly assigned toreceive one or the other treatment. He was disappointed to learnthis, because he assumed that he would receive the bacterialtherapy.Question: Informed consent is legally and ethically required beforesomeone participates in a clinical trial.…What is Cancer Discuss what makes a cell cancerous. Consider the following: Cell Cycle Identical cells Movement of cells Dividing cells Benign and malignant**Radiotherapy (treatment with ionizing radiation) is one of the most effective current cancer treatments. It works by damaging DNA and other cellular components. In which ways could radiotherapy control or cure cancer, and why does radiotherapy often have significant side effects?
- What are stem cells? Which stem cell treatment can form a benign tumor? Please explain how benign tumor can form from the stem cell therapy?1. "What genetic material was used in this research?" 2. How does the completion of this research advance the treatment of cancer? in typed pleaseHow can I study a protein cancer cells?
