Dose= 2Gy, 5 MeV Comments Gamma- Rays Alpha Particles Effect of radiation Direct/Indirect The most probable type of DNA Damage The most important DNA repair mechanism Shape of survival curve RBE (value) LET (value) Cell survival (value)
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- Explain how radiation kill cells. ? please give answer asap and dont copy from anywhereA small fraction—2 to 3%—of all cancers, acrossmany subtypes, displays a quite remarkable phenome-non: tens to hundreds of rearrangements that primarilyinvolve a single chromosome, or chromosomal region.The breakpoints can be tightly clustered, with several in afew kilobases; the junctions of the rearrangements ofteninvolve segments of DNA that were not originally closetogether on the chromosome. The copy number of varioussegments within the rearranged chromosome was foundto be either zero, indicating deletion, or one, indicatingretention.You can imagine two ways in which such multi-ple, localized rearrangements might happen: a progressiverearrangements model with ongoing inversions, deletions,and duplications involving a localized area, or a cata-strophic model in which the chromosome is shattered intofragments that are stitched back together in random orderby nonhomologous end joining (Figure Q20–2).A. Which of the two models in Figure Q20–2 accountsmore readily for the features of…49. Based off of the concept of the COVID-19 vaccination, which of the following conditions is very similar to that same concept used to develop immunity to the COVID-19 virus? a. postinfectious arthritis b. type I diabetes c. lupus d. heart attacks e. grave’s disease
- With current genetic tests, a negative result does notnecessarily rule out future development of a disease, nordoes a positive result always mean that an individual willget the disease. How can we effectively communicate theresults of testing and the actual risks to those being tested?Give a major disadvantage of RAPD as a DNA marker. Provide one (1) recommendation onhow to address this limitation. Briefly discuss. (in 5 sentences only)Many vaccines provide years of protection against a disease. Why doesn't the influenza vaccine offer more than a few months of protection?
- talk about Von willebrand factor test Within two pagesThe family of a sixth-grade boy in Palo Alto, California, wasinformed by school administrators that he would have to transferout of his middle school because they believed his mutation ofthe CFTR gene, which does not produce any symptoms associatedwith cystic fibrosis, posed a risk to other students at the schoolwho have cystic fibrosis. After missing 11 days of school, a settlementwas reached to have the boy return to school. What ethicalproblems might you associate with this example?If 20% of a culture of human cells have a DNA content somewhere between 1 and 2xs (S-phase = 8 hours) and 1X amount of DNA in non-dividing cells, what is the generation time? Show your work if aplicable. A. 25 hours B. 30 hours C. 0.025 hours D. 40 hours E. none of these
- Hi, can you tell me which gene(s) are being mutated in humans due to hepatic exposure to high levels of PCB toxin? Thanks!!In the Western blot shown here, proteins were isolated from redblood cells and muscle cells from two different individuals. Oneindividual was unaffected, and the other suffered from a diseaseknown as thalassemia, which involves a defect in hemoglobin. Theblot was exposed to an antibody that recognizes β globin, whichis one of the polypeptides that constitute hemoglobin. Equal totalamounts of cellular proteins were added to each lane. Explain these results.⦁ Original: ATTTGAGCCMutated: ATTGAGCC. This is an example of what kind of mutation?