Drugs that increase urine flow (diuretic drugs) are oftenemployed in the treatment of hypertension (high blood pressure)or other disease states. Three physiological categories of suchdrugs are ones that (i) function as loop diuretics, (ii) inhibitthe action of aldosterone, and (iii) block Na+ channels in thecollecting ducts. Explain why each of these categories wouldbe expected to increase Na+ excretion and urine flow. (Hint:Rereading the section on hormones at the end of Chapter 28might prove helpful.)

Human Physiology: From Cells to Systems (MindTap Course List)
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ISBN:9781285866932
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Chapter14: The Urinary System
Section: Chapter Questions
Problem 14RE
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Drugs that increase urine flow (diuretic drugs) are often
employed in the treatment of hypertension (high blood pressure)
or other disease states. Three physiological categories of such
drugs are ones that (i) function as loop diuretics, (ii) inhibit
the action of aldosterone, and (iii) block Na+ channels in the
collecting ducts. Explain why each of these categories would
be expected to increase Na+ excretion and urine flow. (Hint:
Rereading the section on hormones at the end of Chapter 28
might prove helpful.)

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