Excerpt from Winzell and Ahren's study: This study characterizes the high-fat diet- fed mouse as a model for impaired glucose tolerance (IGT) and type 2 diabetes. Female mice were fed a high-fat diet (58% energy by fat) or a normal diet (11% fat). Body weight was higher in mice fed the high-fat diet already after the first week, due to higher dietary intake in combination with lower metabolic efficiency. Circulating glucose increased after 1 week on high-fat diet and remained elevated at a level of ~1 mmol/l throughout the 12-month study period. In contrast, circulating insulin increased progressively by time. Question: (A) Why is this study not a prospective study?(B) If you were the researcher, what would you have to do to design it as a as prospective study?

Excerpt from Winzell and Ahren's study: This study characterizes the high-fat diet- fed mouse as a model for impaired glucose tolerance (IGT) and type 2 diabetes. Female mice were fed a high-fat diet (58% energy by fat) or a normal diet (11% fat). Body weight was higher in mice fed the high-fat diet already after the first week, due to higher dietary intake in combination with lower metabolic efficiency. Circulating glucose increased after 1 week on high-fat diet and remained elevated at a level of ~1 mmol/l throughout the 12-month study period. In contrast, circulating insulin increased progressively by time. Question: (A) Why is this study not a prospective study?(B) If you were the researcher, what would you have to do to design it as a as prospective study?

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter38: Introduction To Animal Organization And Physiology

Section: Chapter Questions

Problem 1ITD

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