i need the answer quickly Exercise 2. Determine the indications (contraindications) for theuse of stimulants and blocking cholinergic receptorsFacilities(pharmacologicalgroup)Indications(contraindications)Influence at:eyelexocrineglandssmoothmuscleheartarterialskeletalmuscleorganspressurePilocarpineNeostigmineMethylsulfatePirenzepineIpratropium bromideAzamethoniumbromidePipecuroniumbromide* if the drug does not have a pharmacologically significant effecton the organ, then put "-".

Answered: Image /qna-images/answer/3afe68c1-d770-49f4-b3a7-c2371aa11ac5.jpg

Answered: Exercise 2. Determine the indications…

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

Chapter21: Musculoskeletal And Anti-inflammatory Drugs

Section: Chapter Questions

Problem 14CRQ

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Dear Expert. Thank you for your advice, which is good and helpful. I note that your answer is "when 3 binding sites have been occupied the activity of these receptors is maximum." However, I also note that for a similar question (see below) on α7 nicotinic Acetylcholine Receptor (nAChR) also gives the same answer, ie. at least 3 agonist binding sites should be occupied. Another Question - "To maximize the activity of an α7 nAChR, how many agonist binding sites should be occupied." I understand that in α7 nAChR, binding to two sites is more effective and binding to three sites is most effective for activation. On the other hand, binding to four or five sites in the nAChRs of chromosome 7 speeds up desensitization more than activation. Therefore, to maximize the activity of an α7 nicotinic Acetylcholine Receptor (nAChR) is also "3 sites". Am I right?
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