Explain about familial hypercholesterolemia ?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter4: Basic Immunology And Immunohematology
Section4.7: Rh Typing
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Explain about familial hypercholesterolemia ?

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Introduction:'

Cholesterol is the significant sterol present in the cell membrane of an animal cell. Cholesterol is the building block for other steroid molecules like estrogen, bile salts, testosterone, and progesterone. It is present throughout the lipid bilayer. It is responsible for the stability of the plasma membrane and maintains the membrane's fluidity.

Lipoprotein is a type of globulin (plasma protein). These lipoproteins are of different types, high-density lipoprotein (HDL), low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and chylomicrons. Lipoproteins are used in lipid metabolism and increase in conditions like atherosclerosis, obesity, and liver diseases. 

Cholesterol is carried through the bloodstream by proteins known as lipoproteins.

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