Answered: Explain the difference between a…

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter2: Basic Hematology

Section2.1: Introduction To Hematology

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Explain the difference between a differential white blood cell count and a total white blood cell count.

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The white blood cells are also known as leukocytes are the cells that are a major component of the immune system that helps to protect the body from infections.
The leukocytes contain different types of cells that include neutrophils, eosinophils, basophils that are combinedly known as granulocytes. Furthermore, leukocytes include monocytes and lymphocytes.
The neutrophils constitute 60-70% of leukocytes and are characterized by multilobed nucleus and are effective against bacterial and fungal infections. The granules contain lysozymes.
The eosinophils constitute a 2.3% volume of leukocytes and have a bi-lobed nucleus. The eosinophils are active against larger parasites and they modulate allergic responses in the body.
The basophils constitute a 0.4% volume of leukocyte and consist of a bi-lobed or a tri-lobed nucleus that appears blue after staining. The basophils are responsible for inducing an inflammatory response by releasing histamine.
The lymphocytes are agranulocytes that makeup about 30% volume of leukocytes. The lymphocytes have a major role in adaptive immunity.
The monocytes constitute 5.3% of the total leukocytes and have a kidney-shaped nucleus. The monocytes get differentiated into macrophages and local Kupffer cells.

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