heightened responses to ethanol, and ken&barbie (kb) lack external genitalia. [These are real genes and phenotypes; see links. Only the nomenclature and mapping are fictional for the purpose of this activity.] In the first parental or P₁ generation, homozygous F KB I/F KB / females expressing the lush phenotype (I) and f kb L/Y males expressing fruitless (f) and ken&barbie (kb) were crossed together (artificially, given their reproductively challenged status). The first filial or F₂ female progeny were then bred (with males) resulting in the second filial or F2 generation male progeny (right). 1. F₁ females have phenotypes. & & & Phenotype KB kb 2. Parental, non-cross over genotypes are 3. Single cross-over genotypes are 4. Double cross-over genotypes are 5. The gene in the middle is 6. Recombination frequencies & map distances (% or centiMorgans, cM) are: A. f→ kb B. kb/________ & 7. The most accurate map distance between the outside genes is 8. Illustrate your answers to questions 5-7 on the final map, below: & F F F F f f kb KB L I L I kb L kb I f KB L f KB I C. If & # Flies 27 213 348 912 948 33 177 354 3012

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
10th Edition
ISBN:9781305967359
Author:STARR
Publisher:STARR
Chapter14: Human Inheritance
Section: Chapter Questions
Problem 2GP: Human females have two X chromosomes XX; males have one X and one Y chromosome XY. a. With respect...
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Males of many diploid species (like us) have X and Y sex chromosomes. They are hemizygous for most X-
linked genes. Thus, males express most X-linked alleles, whether they are dominant or recessive in
females. In the fruit fly Drosophila, it is common to achieve the equivalent of a test cross of X-linked
genes in females by assessing the readily observed phenotypes of their male progeny. Since males do
not receive X-linked genes from their father, sires of these crosses can be normal or wild-type flies. In fly
genetics, it is conventional to name a gene after the mutant phenotype that enabled its discovery.
Your challenge is to establish gene order and map distances between three X-linked genes in Drosophila.
Each gene is represented by recessive mutant alleles that express rather distinctive phenotypes relative
to their dominant wild-type alternative alleles. Flies expressing fruitless (f) are bisexual, lush (1) have a
heightened responses to ethanol, and ken&barbie (kb) lack external
genitalia. [These are real genes and phenotypes; see links. Only the
nomenclature and mapping are fictional for the purpose of this activity.]
In the first parental or P₁ generation, homozygous F KB I/F KB I females
expressing the lush phenotype (I) and f kb L/Y males expressing fruitless
(f) and ken&barbie (kb) were crossed together (artificially, given their
reproductively challenged status). The first filial or F₂ female progeny
were then bred (with males) resulting in the second filial or F2 generation
male progeny (right).
1. F₁ females have
2. Parental, non-cross over genotypes are
3. Single cross-over genotypes are
4. Double cross-over genotypes are
5. The gene in the middle is
6. Recombination frequencies & map distances (% or centiMorgans, cM) are:
A. f→ kb.
B. kb 1
7. The most accurate map distance between the outside genes is
8. Illustrate your answers to questions 5-7 on the final map, below:
&
phenotypes.
&
&
&
20
&
Phenotype
KB
kb
F
F
F
F
f
f
f
f
L
I
kb L
KB
I
L
I
kb
kb
KB
KB I
C. If &
# Flies
27
213
348
912
948
33
177
354
3012
Transcribed Image Text:Males of many diploid species (like us) have X and Y sex chromosomes. They are hemizygous for most X- linked genes. Thus, males express most X-linked alleles, whether they are dominant or recessive in females. In the fruit fly Drosophila, it is common to achieve the equivalent of a test cross of X-linked genes in females by assessing the readily observed phenotypes of their male progeny. Since males do not receive X-linked genes from their father, sires of these crosses can be normal or wild-type flies. In fly genetics, it is conventional to name a gene after the mutant phenotype that enabled its discovery. Your challenge is to establish gene order and map distances between three X-linked genes in Drosophila. Each gene is represented by recessive mutant alleles that express rather distinctive phenotypes relative to their dominant wild-type alternative alleles. Flies expressing fruitless (f) are bisexual, lush (1) have a heightened responses to ethanol, and ken&barbie (kb) lack external genitalia. [These are real genes and phenotypes; see links. Only the nomenclature and mapping are fictional for the purpose of this activity.] In the first parental or P₁ generation, homozygous F KB I/F KB I females expressing the lush phenotype (I) and f kb L/Y males expressing fruitless (f) and ken&barbie (kb) were crossed together (artificially, given their reproductively challenged status). The first filial or F₂ female progeny were then bred (with males) resulting in the second filial or F2 generation male progeny (right). 1. F₁ females have 2. Parental, non-cross over genotypes are 3. Single cross-over genotypes are 4. Double cross-over genotypes are 5. The gene in the middle is 6. Recombination frequencies & map distances (% or centiMorgans, cM) are: A. f→ kb. B. kb 1 7. The most accurate map distance between the outside genes is 8. Illustrate your answers to questions 5-7 on the final map, below: & phenotypes. & & & 20 & Phenotype KB kb F F F F f f f f L I kb L KB I L I kb kb KB KB I C. If & # Flies 27 213 348 912 948 33 177 354 3012
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