Hormone release and regulation is a complex interplay of control systems, feedback pathways and the concentration of circulating substances. Demonstrate your understanding of how negative feedback systems work by considering what would happen if the usual mechanisms no longer applied. You may like to think about an ectopic source of adrenocorticotropic hormone (ACTH), as secreted from a small cell carcinoma of the lung, as an example. In your explanation of how negative feedback systems can be derailed, describe how hormone/s released from the target endocrine organ usually regulate the feedback loop.

Biology: The Dynamic Science (MindTap Course List)
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ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
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Chapter42: The Endocrine System
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Hormone release and regulation is a complex interplay of control systems, feedback pathways and the concentration of circulating substances. Demonstrate your understanding of how negative feedback systems work by considering what would happen if the usual mechanisms no longer applied. You may like to think about an ectopic source of adrenocorticotropic hormone (ACTH), as secreted from a small cell carcinoma of the lung, as an example. In your explanation of how negative feedback systems can be derailed, describe how hormone/s released from the target endocrine organ usually regulate the feedback loop.
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