How can we, experimentally, test the relationship between a phenotype or a phenotypic trait and a DNA sequence? a.. amplifying by PCR b. detecting its mRNA c. mutagenesis d. sequencing DNA 19) Which of the following types of bonds are found in the structure of DNA and/or were study objects with radioactivity in the experiments and findings of Hershey and Chase? (two apply) a. peptides (between NH2 and COOH) b. of hydrogens (by electronegativity) c. covalent (shared electrons) d. sulfur (S-S bridges) e) ionic (between positive and negative) 22) The first plant whose genome was sequenced was: a.wheat b.golden rice c.Tomato savor (tomato) d. Arabidopsis thaliana

How can we, experimentally, test the relationship between a phenotype or a phenotypic trait and a DNA sequence? a.. amplifying by PCR b. detecting its mRNA c. mutagenesis d. sequencing DNA 19) Which of the following types of bonds are found in the structure of DNA and/or were study objects with radioactivity in the experiments and findings of Hershey and Chase? (two apply) a. peptides (between NH2 and COOH) b. of hydrogens (by electronegativity) c. covalent (shared electrons) d. sulfur (S-S bridges) e) ionic (between positive and negative) 22) The first plant whose genome was sequenced was: a.wheat b.golden rice c.Tomato savor (tomato) d. Arabidopsis thaliana

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter19: Genomes And Proteomes

Section: Chapter Questions

Problem 1TYK

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"Chargaff's rules" about the composition of bases in DNA dictates that A. the sum of purine residues must equal the sum of pyrimidine residues. B. the sum of A-T base pairs must equal the sum of G-C base pairs. C. the base composition of DNA is the same in all species. D. DNA specimens isolated from different tissues of the same species vary in base composition.
a. Which gene is mutated in individuals with sickle-cell anemia? b. What are the major symptoms of this disorder? c. What was the first published scientific description of sickle-cell anemia? d. Describe two other features of this disorder that you learned from the OMIM database and state where in the database you found this information
Xeroderma pigmentosum is a genetic disease caused by an error in the nucleotide excision repair process that fixes damage to DNA by ultraviolet light. Studies have shown that it can result from mutations in any one of seven genes. What can you infer from this finding? A) There are seven genes that produce the same protein B) These seven genes are the most easily damaged by ultraviolet light. C) There are seven enzymes involved in the nucleotide excision repair process. D) These mutations have resulted from translocation of gene segments.
1. a) What does DNA stand for? b)What is the name of the DNA structure?
The original DNA base sequence is 5’-AGCGTTACCGT-3’; a mutation in the DNA strand results in the base sequence 5’-AGGCGTTACCGT-3’. What can you conclude about the mutation? A. It is a frameshift mutation. B. It is a silent mutation. C. It is a deleterious mutation. D. It may result in a single amino acid change in the protein being coded for by this base sequence.
1. The image below shows the base cytosine and a methylated form of cytosine that occurs frequentlyin the human genome. Use your knowledge of DNA structure to answer these questions: a. Does methylation of cytosine affect its ability to base-pair with guanine? Explain. b. Could methylation of cytosine affect the binding of a protein that interacts with a C-G basepair in the major groove? Explain your answer.
1a) Why is it possible for you to study the eye colour gene by extracting cheek cells? a. Because the nucleus of every cell in the human body contains the same genetic information. b. Because the cheek cells are located near the cells of the eye and so they are able to exchange DNA. c. Because all genes in the human body are expressed at all times so it is easy to study them. d. All of the above are possible explanations. 1b) What is the purpose of heating the sample to 75°C following addition of the 0.2M NaOH solution? a. To denature the histone proteins that are keeping the DNA tightly coiled. b. To ensure that all the DNA is removed from the swab in preparation for PCR. c. To breakdown the cheek cell membrane to release the DNA from the cell. d. It breaks down the circular DNA down into linear fragments so that they will be easier to visualize.i
Chargaff's analysis of the relative base composition of DNA showed us that a. The amount of adenine is equivalent to cytosine, and thymine is equivalent to guanine b. The amount of purines is equivalent to the amount of pyrimidines c. All four nitrogenous bases occur in equal amounts in DNA d. The base composition of a species' DNA is random e. None of the above are true
a. This piece of DNA is cut by EcoRI, the resulting fragments are separated by gel electrophoresis, and the gel is stained with ethidium bromide. Draw a picture of the bands that will appear on the gel. b. If a mutation that alters EcoRI site 1 occurs in this piece of DNA, how will the banding pattern on the gel differ from the one that you drew in part a? c. If mutations that alter EcoRI sites 1 and 2 occur in this piece of DNA, how will the banding pattern on the gel differ from the one that you drew in part a? d. If 1000 bp of DNA were inserted between the two restriction sites, how would the banding pattern on the gel differ from the one that you drew in part a? e. If 500 bp of DNA between the two restriction sites were deleted, how would the banding pattern on the gel differ from the one that you drew in part a?
Please answer the following question and explain Q1. If MacLeod and McCarty had accidentally contaminated their RNase enzyme with DNase, how would this have changed the conclusion that they made from their experiments? Pick the correct letter option A. They would have concluded that DNA is the only molecule required for genetic transformation. B. They would have concluded that DNA and protein are both required for genetic transformation. C. They would have concluded that RNA is the only molecule required for genetic transformation. D. They would have concluded that RNA and DNA are both required for genetic transformation. E. They would have concluded that proteins are the only molecules required for genetic transformation
Refer to Figure 2 and compare this with the DNA model in Figure 1. a. In what ways are they similar? b. In what ways are they different? c. What is the biological significance of such differences? Why is the DNA referred to as the genetic material?
(a) What is meant by the term base pairing?(b) Which bases pair with which other bases?(c) How many hydrogen bonds does each base pair have?