I II II A

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
Problem 27CRQ
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The following pedigree traces the inheritance of a certain genetic disease in a family. The circles represent women and the squares represent men. Individuals with darkened shapes have the disease, while individuals with white shapes do not. The lines indicate the relationship between individuals, either through marriage or by birth. Study the chart and then answer the question.
 
How many women have the disease in this pedigree?
 
Five
 
One
 
Four
I
II
II
A
Transcribed Image Text:I II II A
Expert Solution
Step 1: Introduction

The genes located on the nuclear chromosomes obey the Mendelian law of inheritance. In the human being, the nuclear genome carries most of the generation information of the individual which gets inherited from one generation to the next generation.

The pedigree is the family tree diagram used to represent the pattern of inheritance in the family. The pedigree is a diagrammatic representation of the inheritance of genes across the family. In pedigree, the female is represented by a circle while the square use to represent the male. The pedigree analysis helps to analyze the existing data when there is no possibility to perform the controlled crosses. Pedigrees are most applicable for Human genetics, which helps to reveal the inheritance of genes in humans in many generations
 

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