In animal husbandary,if two closely related animals are mated for a few generation,it result in loss of fertility and vigour.why is this so?

Science Of Agriculture Biological Approach
5th Edition
ISBN:9780357229323
Author:Herren
Publisher:Herren
Chapter11: Animal Reproduction
Section: Chapter Questions
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In animal husbandary,if two closely related animals are mated for a few generation,it result in loss of fertility and vigour.why is this so?

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