It was stated that the Rh antigens are so sparsely scattered on the red cell surface that lgG molecules bound to the Rh antigens are too far apart to fix C1q. Therefore, complement-mediated hemolysis cannot be invoked to explain hemolytic disease of the newborn. By what mechanism are the red cells destroyed?

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter42: The Immune System
Section: Chapter Questions
Problem 3VCQ: Figure 42.16 The Rh antigen is found on Rh positive red blood cells. An Rh-negative female can...
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1 It was stated that the Rh antigens are so sparsely scattered on the red cell
surface that IgG molecules bound to the Rh antigens are too far apart to fix C1q.
Therefore, complement-mediated hemolysis cannot be invoked to explain hemolytic
disease of the newborn. By what mechanism are the red cells destroyed?
Transcribed Image Text:1 It was stated that the Rh antigens are so sparsely scattered on the red cell surface that IgG molecules bound to the Rh antigens are too far apart to fix C1q. Therefore, complement-mediated hemolysis cannot be invoked to explain hemolytic disease of the newborn. By what mechanism are the red cells destroyed?
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