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- Discuss the actions of sulfanilamide and trimethoprim as antimetabolite.Summarize the mechanism of action and the therapeutic use of the following antifungal drugs: miconazole, nystatin, griseofulvin, amphotericin B, and 5-flucytosine.Which of the following drugs have a neurotoxic metabolite and predispose toseizures?A) Lorazepam.B) Meperidine.C) Oxycodone. D) B+C.E) all of the above.