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Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter3: The Plasma Membrane And Membrane Potential
Section: Chapter Questions
Problem 2TAHL: Assume that a membrane permeable to Na+ but not to Cl- separates two solutions. The concentration of...
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9. A cell membrane at 37°C is found to be permeable to Ca²+ but not to anions, and analysis
shows the inside concentration to be 0.200 M and the outside concentration to be 0.005 M
in Ca?+.
a) What potential difference in volts would have to exist across the membrane for Ca?+
to be in equilibrium at the stated concentrations? Assume that activity coefficients are equal
to 1. Give the sign of the potential inside with respect to that outside.
b) If the measured inside potential is +100 mV with respect to the outside, what is the
minimum (reversible) work required to transfer 1 mol of Ca²+ from outside to inside under
these conditions?
Transcribed Image Text:9. A cell membrane at 37°C is found to be permeable to Ca²+ but not to anions, and analysis shows the inside concentration to be 0.200 M and the outside concentration to be 0.005 M in Ca?+. a) What potential difference in volts would have to exist across the membrane for Ca?+ to be in equilibrium at the stated concentrations? Assume that activity coefficients are equal to 1. Give the sign of the potential inside with respect to that outside. b) If the measured inside potential is +100 mV with respect to the outside, what is the minimum (reversible) work required to transfer 1 mol of Ca²+ from outside to inside under these conditions?
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