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- explain in detail what the pathogensis may be for a A 25-year-old female pateint presented to her 28-week antenatal appointment with the complaint of lethargy, who was also noted pale but was diagnosed with microsytic anemia. give full pathogensis. explain more the 1 cause in detail. 600 wordsPatient X- diagnosed with G6PD deficiency since birth, was prescribed with cotrimoxazole for UTI. She did not reveal her diagnosis to her physician. After 3 days, she began experiencing paleness and easy fatigability, when she went back for a follow-up, her RBC count was low. Which sets of laboratory and diagnostic parameters must be done to monitor the patient’s response to therapy? a. CBC, urinalysis, WBC with differentials and electrolytes b. CBC, urinalysis, serum creatinine, WBC differential, ALT c. CBC, urinalysis, fecalysis, ECG, ALT and AST, d.CBC, urinalysis, serum creatinine, ECGCASE STUDY Ruth, a 25 year office worker, decided to visit the doctor’s office after noticing changes in her body. She complained of severe nausea, vomiting, stomach pains and loss in appetite. But her biggest worries are her frequent skin itching, bloated belly and apparent yellowish pallor. After physically examining Ruth, the doctor ordered several laboratory tests. These include CBC, Coagulation studies, blood chemistry and Serologic tests. The results showed Prolonged Prothrombin time, increased INR, decreased blood proteins such as albumin, elevated liver enzymes and bilirubin levels. Her serology was reactive for the Hepatitis B surface antigen, positive for Total anti-HBc but negative for the anti-HBe and anti-HBs Answer the following questions, using the medical information of Ruth. 1. What do you think is the health issue of Ruth? Provide medical evidence.
- CASE STUDY Ruth, a 25 year office worker, decided to visit the doctor’s office after noticing changes in her body. She complained of severe nausea, vomiting, stomach pains and loss in appetite. But her biggest worries are her frequent skin itching, bloated belly and apparent yellowish pallor. After physically examining Ruth, the doctor ordered several laboratory tests. These include CBC, Coagulation studies, blood chemistry and Serologic tests. The results showed Prolonged Prothrombin time, increased INR, decreased blood proteins such as albumin, elevated liver enzymes and bilirubin levels. Her serology was reactive for the Hepatitis B surface antigen, positive for Total anti-HBc but negative for the anti-HBe and anti-HBs 1. What do you think caused the liver disease of Ruth? Explain your answer2. What other hepatitis virus can infect Ruth?3. Is it an acute or a chronic infection? Explain your answer10. A 64-year-old woman, Mrs. Sharmila is brought to the emergency room, with a 3-day history of fever, worsening confusion, agitation, and disorientation. Her husband says that he also noticed drooping of her mouth on the left side, since this morning and immediately rushed her to the hospital. She has no other significant past history and no recent foreign travel. Examination reveals a pulse rate of 90 per minute, BP of 142/90 mm of Hg, and a temperature of 100.3F. She is drowsy and agitated but is able to follow directions. She has some neck rigidity. Weakness is present on the left side of the face with drooping of the angle of the mouth, inability to close her eyelids, and inability to furrow her forehead on the same side. The rest of the neurological examination is normal. CSF tap is performed and the lab results are attached below. What is the most likely causative agent in this condition?(59) A 60-year old woman with type-2 diabetes mellitus comes to the physician because of a 6-week history of a progressive rash under both breasts. She says that the rash irritability responded to use of an over-the-counter topical preparation containing clotrimazole, but the treatment has recently has become ineffective in relieving her symptoms. Physical examination shows a 10-cm of erythema with a mucous discharge under each breast. Her finger stick blood glucose concentration is 115 mg/dL. Microscopic examination of the discharge shows branching hyphae. The physician suspects that the causal organism in this patient is resistant to clotrimazole. Alterations in which of the following microbial cell binding sites is the most likely cause of this resistance? (A) Lanosterol demethylase (B) Peptidyl transferase (C) Thymidine kinase (D) Topoisomerase IV (E) uridine kinase
- Pt is a 55 y.o female with past medical history of end-stage renal disease on hemodialysis via perm catheter, hypertension, hyperlipidemia, type 2 diabetes, anemia of chronic disease, peripheral neuropathy, recurrent C.Difficile. History of Acinetobacter bacteremia come into the hospital as direct transfer from Newport given worsening pleural effusion of importance. Pt was recently admitted at Rhode Island Hospital and discharged a few weeks ago after being diagnosed with necrotizing pneumonia. lung disease abscess on CT scan. She underwent BAL and culture grew klebsiella oxytocin which she was treated with Augmentin for 6weeks duration. She had elevated 1,3 Beta D flu an but was deemed to be potentially false positive. She was also found to have Acinetobacter growing from dialysis catheter too and the catheter was removed on 3/8 and a new one was replaced on 3/9. Unfortunately came back from Newport hospital because of progressively worsening shortness of breath as well as well as…Pt is a 55 y.o female with past medical history of end-stage renal disease on hemodialysis via perm catheter, hypertension, hyperlipidemia, type 2 diabetes, anemia of chronic disease, peripheral neuropathy, recurrent C.Difficile. History of Acinetobacter bacteremia come into the hospital as direct transfer from Newport given worsening pleural effusion of importance. Pt was recently admitted at Rhode Island Hospital and discharged a few weeks ago after being diagnosed with necrotizing pneumonia. lung disease abscess on CT scan. She underwent BAL and culture grew klebsiella oxytocin which she was treated with Augmentin for 6weeks duration. She had elevated 1,3 Beta D flu an but was deemed to be potentially false positive. She was also found to have Acinetobacter growing from dialysis catheter too and the catheter was removed on 3/8 and a new one was replaced on 3/9. Unfortunately came back from Newport hospital because of progressively worsening shortness of breath as well as well as…Pt is a 55 y.o female with past medical history of end-stage renal disease on hemodialysis via perm catheter, hypertension, hyperlipidemia, type 2 diabetes, anemia of chronic disease, peripheral neuropathy, recurrent C.Difficile. History of Acinetobacter bacteremia come into the hospital as direct transfer from Newport given worsening pleural effusion of importance. Pt was recently admitted at Rhode Island Hospital and discharged a few weeks ago after being diagnosed with necrotizing pneumonia. lung disease abscess on CT scan. She underwent BAL and culture grew klebsiella oxytocin which she was treated with Augmentin for 6weeks duration. She had elevated 1,3 Beta D flu an but was deemed to be potentially false positive. She was also found to have Acinetobacter growing from dialysis catheter too and the catheter was removed on 3/8 and a new one was replaced on 3/9. Unfortunately came back from Newport hospital because of progressively worsening shortness of breath as well as well as…
- A 29 years old female, married, G1PO AOG 16 weeks, complained of vague abdaminal wall pain for 3 days, with slight fever and urgency. She took Paracetamol 500 mg and there was temporary relieved of symptoms. A few minutes prior to consultation, she noticed blood tinged urine. Husband is an overseas worker (Seaman). What is the probable clinical impression on consultation? Acute cystitis. hemorrhagic Acute pyclonephritis complicated Acute pyelonephritis uncomplicated Acute urethritis syndromeQuestion:- A 25-year-old man comes to the emergency department because of a 2-day history of fever and rash. He has a history of complex partial sezure secondary to an arteriovenous malformation. He has had breath through seizure several times each despite treatment with several medication regions. Initially, treatment with phenytoin, which caused sedation. Two weeks ago, he was stitched to valproic acid and lamotrigine. He states that he has not had any seizure during topiramate and phenytoin, which caused sedation. Two weeks ago, he was switched valproic acid and lamotrigine. He states that he was not ad nay seizure during this time, and he finished his sample package of lamotrigine. He is awake and alert but appears ill. Vital signs are temperature 39.0 oC (102.2 oF), pulse 1110/min, respiration 22/min. and blood pressure 130/90 mm Hg. Examination shows extensive bullae, especially over the hands and feet. There are erosive lesions over the mouth and genital area. Which of the…30) A 45-year-old man is evaluated by his primary care physician for complaints of early satiety and weight loss. On physical examination,his spleen is palpable 10 cm below the left costal margin and is mildly terder to palpation. His laboratory studies show a leukocyte count of 125,000/Ml with a differential of 80% neutrophils, 9% bands, 3% myelocytes, 3% metamyelocytes,1% blasts, 1% lymphocytes, 1% eosinophils, and 1% basophils. Hemogicbin is 8.4 g/dL, hematocrit 26.8% ,and platelet count is 668,000/uL. A bone marrow biopsy demonstrates increased celluarity with an increased myeloid to erythroid ratio. Which of the following cytogenetic abnormalities is most likey to be found in this patient? A Deletion of a portion of the long arm of chromosome 5, del(5q) B Inversion of chromosome 16,inv(16) C Reciprocal translocation between chromosomes 9 and 22 (Philadelphia chromosome D Translocations of the long arms of chromosomes 15 and 17 E Trisomy 12