Pharmaceuticals When a medicine is administered orall
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Q: What is meant by "selective toxicity"
A: The explanation is given below.
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- Nitric oxide is broken down very quickly after its release. Why?A stock solution of drug Y is available at 10%w/v. You need to dilute this with Syrup, BP in order to supply a patient with a solution containing 5mg/mL of drug Y. Assuming no volume displacement effects, what is your formula for the preparation of 100 mL of the final solution?The amount of calcium in physiologic fluids can be determined by a complexometric titration with EDTA. In one such analysis, a 0.100-mL sample of blood serum was made basic by adding 2 drops of NaOH and titrated with 0.001 M EDTA, requiring 0.238 mL to reach the end point. Report the concentration of calcium in the sample as miligrams of Ca per 100 mL. (Ca = 40.078 amu).
- Calculation at the initial point of a complexation titration: What is the pSr value of a 50.00 mL solution of 0.01000 M Sr2+ (formation constant, Kf = 5.348 x 108) after the addition of 0.00 mL of 0.02000 M EDTA which was buffered to pH 11.00? Round your final answer to two decimal places to the right of the decimal point.KCI for injection contains 40 mEq in 20 mL. An order requires 15 mEq, how many mL are needed?Calculations Involving Units, mcg/mg and Other Measurement of Potency. Show your complete solution. 1. A hospital pharmacy has available 2-mL prefilled syringes containing 80 mg of tobramycinand 1.5-mL prefilled syringes containing 60 mg of tobramycin. The syringes are calibratedin 0.25-mL units. Explain how you would prepare a medication order calling for 110 mgof tobramycin to be added to 100 mL of D5W for intravenous infusion.
- A neonate patient weighing 3,821 grams is prescribed gentamicin 6 mg/kg in D5W for IV infusion. If the concentrated gentamicin injection contains gentamicin 10mg/mL, how many milliliters of gentamicin injection should be added to the dextrose? Round your answer to the nearest tenth of a milliliter.Calculation at the pre-equivalence point region of a complexation titration: What is the pSr value of a 50.00 mL solution of 0.01000 M Sr2+ (formation constant, Kf = 5.348 x 108) after the addition of 11.7 of 0.02000 M EDTA which was buffered to pH 11.00? Round your final answer to two places to the right of the decimal point.Calculate the concentration of an EDTA solution of which 24.22 mL were needed to titrate the Ca2+ions present in a 50.00 mL solution containing 246.7 mg CaCO3. Express your answer in terms of (a) molar concentration of EDTA (b) Ca Titer (mg Ca per mL of EDTA) MM Ca= 40.078 solve it in a way that it is in one equation already and cancelling all the values just like given in th epicture
- Calculate the following concentration given thisPredict the diffusivity of human serum albumin at 293 K in water as a dilute solution and compare it with experimental data. Assume the following: The molecular weight of human serum albumin, MA= 72,300 kg/kmol The viscosity of water at 293 K is 0.897 x 10-3 Pa∙s The experimental data value is 5.93 x 10-11 m2/s.3. Astelin nasal spray contains 0.1% azelastine hydrochloride and 400 µg/mL of benzalkonium chloride as a preservative. A container is capable of delivering 200 metered sprays of 0.137 mL each. The percent concentration of benzalkonium chloride in the preparation is ________ %, and this is equivalent to a ratio strength of 1:2500 w/v. True or False?
