Question 33 Orciprenaline (C₁H₁7NO3, 211.258 g/mol) is a bronchodilator used in the treatment of asthma. The BP assay for orciprenaline tablets is described below. "Weigh and powder 20 tablets. Shake a quantity of the powder containing 80 mg of orciprenaline sulphate with 50 mL of 0.01 M hydrochloric acid (HCI), filter and add sufficient 0.01 M HCI to the filtrate to produce 100 mL. The following information was obtained during the assay: Weight of 20 tablets = 2.5564 g HO Weight of tablet powder assayed = 0.5266 g Absorbance reading = 0.5868 Stated content per tablet = 20 mg A (1%, 1 cm) at 276 nm = 72.3 OH Orciprenaline Dilute 10 mL to 100 mL with 0.01 M HCl and measure the absorbance of the resulting solution at the maximum at 276 nm." OH H N

Question 33 Orciprenaline (C₁H₁7NO3, 211.258 g/mol) is a bronchodilator used in the treatment of asthma. The BP assay for orciprenaline tablets is described below. "Weigh and powder 20 tablets. Shake a quantity of the powder containing 80 mg of orciprenaline sulphate with 50 mL of 0.01 M hydrochloric acid (HCI), filter and add sufficient 0.01 M HCI to the filtrate to produce 100 mL. The following information was obtained during the assay: Weight of 20 tablets = 2.5564 g HO Weight of tablet powder assayed = 0.5266 g Absorbance reading = 0.5868 Stated content per tablet = 20 mg A (1%, 1 cm) at 276 nm = 72.3 OH Orciprenaline Dilute 10 mL to 100 mL with 0.01 M HCl and measure the absorbance of the resulting solution at the maximum at 276 nm." OH H N