QUESTION: Gaucher disease is caused by a chronic enzyme deficiency. Greg has a sister afflicted with the disease. His parents, grandparents, and his other sister and two brothers are not affected. Discussions with relatives in his wife’s family reveal that her paternal grandmother has a brother afflicted by this disease. If the frequency of the disease allele is 0.16 in this population, what is the chance that Greg’s unaffected sister has an affected child?

QUESTION: Gaucher disease is caused by a chronic enzyme deficiency. Greg has a sister afflicted with the disease. His parents, grandparents, and his other sister and two brothers are not affected. Discussions with relatives in his wife’s family reveal that her paternal grandmother has a brother afflicted by this disease. If the frequency of the disease allele is 0.16 in this population, what is the chance that Greg’s unaffected sister has an affected child?

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter1: Numerals And Fractions

Section: Chapter Questions

Problem 5PP

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