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- true or false Aldosterone is required to restore water from loop of Henle, and reabsorption of Na+ from this segment is increased by ADH, allowing equilibration of water with the hyperosmotic interstitiumSome tumors of the adrenal cortex secrete excess aldosterone and may cause paralysis. Explain this effect andidentify the electrolyte and fluid imbalances you wouldexpect to observe in such a caseThe reabsorption of water, Cl–, and glucose by the PCT islinked to the reabsorption of Na+, but in three very different ways. Contrast these three mechanisms
- In response to hemorrhagic shock, the kidneys produce a small volumeof very concentrated urine. Explain how the rate of filtrate formationchanges and how Na+ transport is altered in the distal convoluted tubulein response to hemorrhagic shock.What effect does aldosterone have on Na+ verses K+ in the DCTExplain the interactions between ADH, angiotensin-renin-aldosterone P, GFR, in a patient with acute hemorrhage.
- The long-term regulation of arterial blood pressure is controlled by the Renin-Angiotensin-Aldosterone system (RAA system). Explain how the activation of the RAA system is initiated.The renin-angiotensin-aldosterone system can be inhibited in orderto reduce high blood pressure. Usually, the angiotensin-convertingenzyme, which converts angiotensin I to angiotensin II, is inhibitedby drug therapy. Why would this enzyme be an effective point todisrupt the system?The relationship between ADH and the tubular re-absorbtion of water?
- Renal tubules cannot reabsorb HCO3–; yet HCO3–concentration in the tubular fluid falls while in the blood plasma itrises. Explain this apparent contradiction.True or false activation of the angiotensin in Cascade increases blood volume by increasing the reabsorption of NA+ CL- in the kidneysExplain the effect of the renin-angiotensin-aldosteronesystem on water-salt balance.
