Sex hormone secretion is governed by a negative feedback loop to the hypothalamus and pituitary, similar to that for thyroid hormone or cortisol. Because of this, a veterinarian can use a blood test to find out whether a female dog has been neutered. Dogs who still have their ovaries have a lower blood level of luteinizing hormone (LH) than dogs who have been neutered. Explain why removing a dog’s ovaries would result in an elevated level of LH.

Body Structures & Functions
12th Edition
ISBN:9781285695495
Author:Scott
Publisher:Scott
Chapter11: Endocrine Systems
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Sex hormone secretion is governed by a negative feedback loop to the hypothalamus and pituitary, similar to that for thyroid hormone or cortisol. Because of this, a veterinarian can use a blood test to find out whether a female dog has been neutered. Dogs who still have their ovaries have a lower blood level of luteinizing hormone (LH) than dogs who have been neutered. Explain why removing a dog’s ovaries would result in an elevated level of LH.  
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