The Hoffman rule states that: the alkene with less alkyl substituents is the major product in base-induced elimination reactions the more highly substituted carbocation is formed as the intermediate rather than the less highly substituted one the alkene with more alkyl substituents is the major product in base-induced elimination reactions the less highly substituted carbocation is formed as the intermediate rather than the more highly substituted one
The Hoffman rule states that: the alkene with less alkyl substituents is the major product in base-induced elimination reactions the more highly substituted carbocation is formed as the intermediate rather than the less highly substituted one the alkene with more alkyl substituents is the major product in base-induced elimination reactions the less highly substituted carbocation is formed as the intermediate rather than the more highly substituted one
Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Chapter2: The Chemical Level Of Organization
Section: Chapter Questions
Problem 43CTQ: If the disaccharide maltose is formed from two glucose monosaccharides, which are hexose sugars, how...
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43. The Hoffman rule states that:
- the
alkene with less alkyl substituents is the major product in base-induced elimination reactions - the more highly substituted carbocation is formed as the intermediate rather than the less highly substituted one
- the alkene with more alkyl substituents is the major product in base-induced elimination reactions
- the less highly substituted carbocation is formed as the intermediate rather than the more highly substituted one
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