THE MOLECULAR GENETICS OF CYSTIC FIBROSIS The following is the base sequence of DNA that codes for amino acids 506-510 of the protein that regulates the chlorine channels in the cell membrane. This protein contains a total of 1476 amino acids so this is a small part of the entire gene. DNA Template Strand: 3'TAGTAGAAACCACAA5' 1. What is the minimum number of DNA nucleotides in this whole gene? 2. What is the sequence of bases on the strand of DNA that is complementary to the template strand? 3. What mRNA will be formed from the template strand of DNA? 4. What amino acids will this mRNA code for?

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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THE MOLECULAR GENETICS OF CYSTIC FIBROSIS and of
The following is the base sequence of DNA that codes for amino acids
506-510 of the protein that regulates the chlorine channels in the cell
membrane. This protein contains a total of 1476 amino acids so this is a
small part of the entire gene.
DNA Template Strand: 3'TAGTAGAAACCACAA5'
1. What is the minimum number of DNA nucleotides in this whole
gene?
2. What is the sequence of bases on the strand of DNA that is
complementary to the template strand?
3. What mRNA will be formed from the template strand of DNA?
4. What amino acids will this mRNA code for?
5. If the 6th, 7th and 8th bases in the template strand of the DNA are
removed, rewrite the new template strand below.
6. When the template strand of the DNA is changed, this is referred to
as a mutation. What kind of mutation is this?
65
Transcribed Image Text:THE MOLECULAR GENETICS OF CYSTIC FIBROSIS and of The following is the base sequence of DNA that codes for amino acids 506-510 of the protein that regulates the chlorine channels in the cell membrane. This protein contains a total of 1476 amino acids so this is a small part of the entire gene. DNA Template Strand: 3'TAGTAGAAACCACAA5' 1. What is the minimum number of DNA nucleotides in this whole gene? 2. What is the sequence of bases on the strand of DNA that is complementary to the template strand? 3. What mRNA will be formed from the template strand of DNA? 4. What amino acids will this mRNA code for? 5. If the 6th, 7th and 8th bases in the template strand of the DNA are removed, rewrite the new template strand below. 6. When the template strand of the DNA is changed, this is referred to as a mutation. What kind of mutation is this? 65
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