The new DNA codon would be GAT. This would code for the mRNA codon CUA, which would translate into the amino acid leucine. This is a silent mutation because there is no change in the amino acid being coded for at this position, so the polypeptide remains the same. The new DNA codon would be AAG. This would code for the mRNA codon, UUC, which would translate into the amino acid phenylalanine. This would cause a missense mutation, since the amino acid that should be there-valine- gets replaced with phenylalanine. The new DNA codons for the fifth, sixth, seventh, and eighth codons are AAC, CCC, UCC, AA. This results in asparagine, proline, serine and no amino acid as the last four. This is a frameshift mutation so every codon after this is affected. 1. The second DNA codon, CAG, has a substitution in its first nucleotide, with A replacing C. 2. The fifth DNA codon, TGT, has a deletion of the G. 3. The seventh DNA codon, GAG, has a substitution in its third nucleotide, with T replacing G.

Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN:9781337408332
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter9: From Dna To Protein
Section: Chapter Questions
Problem 8SQ
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Solve 7. Using the ß-hemoglobin DNA sequence shown here and the genetic code provided in the table match the following to explain the changes that you would predict based on the mutations. 

DNA
codon
(5-3)
mRNA
codon
Amino
acid
TAC
CAG
GTA
GAC
AUG
GUC CAU
CUG
Methionine Valine Histidine Leucine
TGT
GGG
GAG
GTT
ACA
CCC CUC
CAA
Threonine Proline Leucine Glutamate
Transcribed Image Text:DNA codon (5-3) mRNA codon Amino acid TAC CAG GTA GAC AUG GUC CAU CUG Methionine Valine Histidine Leucine TGT GGG GAG GTT ACA CCC CUC CAA Threonine Proline Leucine Glutamate
The new DNA codon would
be GAT. This would code
for the mRNA codon CUA,
which would translate into
the amino acid leucine. This
is a silent mutation because
there is no change in the
amino acid being coded for
at this position, so the
polypeptide remains the
same.
The new DNA codon would
be AAG. This would code
for the mRNA codon, UUC,
which would translate into
the amino acid
phenylalanine. This would
cause a missense mutation,
since the amino acid that
should be there-valine-
gets replaced with
phenylalanine.
The new DNA codons for
the fifth, sixth, seventh, and
eighth codons are AAC,
CCC, UCC, AA. This results
in asparagine, proline,
serine and no amino acid as
the last four. This is a
frameshift mutation so
every codon after this is
affected.
1. The second DNA codon, CAG, has a
substitution in its first nucleotide,
with A replacing C.
2. The fifth DNA codon, TGT, has a
deletion of the G.
3. The seventh DNA codon, GAG, has
a substitution in its third nucleotide,
with T replacing G.
Transcribed Image Text:The new DNA codon would be GAT. This would code for the mRNA codon CUA, which would translate into the amino acid leucine. This is a silent mutation because there is no change in the amino acid being coded for at this position, so the polypeptide remains the same. The new DNA codon would be AAG. This would code for the mRNA codon, UUC, which would translate into the amino acid phenylalanine. This would cause a missense mutation, since the amino acid that should be there-valine- gets replaced with phenylalanine. The new DNA codons for the fifth, sixth, seventh, and eighth codons are AAC, CCC, UCC, AA. This results in asparagine, proline, serine and no amino acid as the last four. This is a frameshift mutation so every codon after this is affected. 1. The second DNA codon, CAG, has a substitution in its first nucleotide, with A replacing C. 2. The fifth DNA codon, TGT, has a deletion of the G. 3. The seventh DNA codon, GAG, has a substitution in its third nucleotide, with T replacing G.
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