There are a number of conserved sequences found in an mRNA that dictate where splicing occurs. Where are these sequences found relative to the exon-intron junctions? What is the significance of these sequences in the splicing process? One of these important regions is the branch point A found in the intron. What is the role of the branch point A in the splicing process, and can this be accomplished with the OH group on either the 2′ or the 3′ carbon?

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter16: Gene Expression
Section: Chapter Questions
Problem 18RQ: IS. Alternative splicing has been estimated to occur in more than 95% of multi-exon genes. Which of...
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There are a number of conserved sequences found in an mRNA that dictate where splicing occurs. Where are these sequences found relative to the exon-intron junctions? What is the significance of these sequences in the splicing process? One of these important regions is the branch point A found in the intron. What is the role of the branch point A in the splicing process, and can this be accomplished with the OH group on either the 2′ or the 3′ carbon?

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