2.Thiopurine methyltransferase (TPMT) metabolizes many immunosuppressants such asazathioprine. Genetic polymorphism changes the activity of this enzyme and thus themetabolic rate of transforming of drugs their corresponding metabolites.Define what the genetic polymorphism is.а.If a genetic variation leads to a reduction of TPMT activity, explain what outcomes willbe expected to azathioprine.b.

Thiopurine S-methyltransferase (TPMT) deficiency is a disorder in which the activity of an enzyme…

Answered: Thiopurine methyltransferase (TPMT)…

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

Chapter25: Cardiovascular Drugs

Section: Chapter Questions

Problem 13CRQ

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2. Please describe the medication interaction between clonidine and atenolol. Please reply soon. Should the response mention the causes and mechanism?
1 Which of the following is a contraindication to the antiarrhythmic Amiodarone? A) Tachycardia B) Allergy to Lidocaine C) Bradycardia D) Hypertension 2 Which of the following is a common side effect of cholesterol medication? A) Muscle pain B) Diabetes C) Headache D) Decreased urination 3 Which of the following most accurately describes the mechanism of action of a "statin"? A) Inhibits platelet aggregation B) Inhibits sodium excretion in the kidneys C) Inhibits cholesterol production in the liver D) Inhibits sodium reabsorption in the loop of Henle 4 Which of the following is an indication to the antiarrhythmic Amiodarone? A) Bradycardia B) Hypercalcemia C) Hypertension D) Supraventricular Tachycardia (SVT)
(4). How can these pathological factors listed below affect drug effects? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfunction.
5. What conditions should not be used with Cetirizine?
2. The physician orders Mr. Baletbet to also receive diphenhydramine with her metoclopramide. What is the rationale for giving these two medications together? In short I need to understand.
5. A physician orders Vistaril 50 mg IM stat for a patient with pruritus (itching). The patient weighs 132 pounds. A. What is the recommended dosage range in mg for this patient? B. Is the dose safe as ordered? C. How many mL of Vistaril should be injected? D. What is the maximum recommended mg per day?
7. What are some potential causes of the adverse symptoms that some patients used ACE inhibitors for?
1) What is the importance of good nutrition in the efforts of containing Covid-19 in Ghana
1. What is the medical science concerned with the use of drugs in the treatment of disease? * a Pharmacotherapeutics b Pharmacology c Pharmacoepidemiology Pharmacognosy d Pharmacogenetics 2 Which of the following is ACCURATE about Reboxetine? * a MAO inhibitor b Noradrenaline reuptake inhibitor c Adrenergic agonist d Cholinergic agonist e Selective serotonin reuptake inhibitor 3 In Graded Dose-Response, which of the following parameters refers to the dose producing 50% of the maximum response? * a Potency b LD50 c Efficacy d Ceiling dose e ED50 4 Which of the following statements best describe a partial agonist? * a Interacts with more than one receptor type b Blocks the effect of the antagonist c Cannot produce the full effect even at high doses d Has low potency but high efficacy. e Has affinity but lacks efficacy 5 Which drug promotes transient muscle fasciculation followed by muscle paralysis that is not reversed by Neostigmine? * a Hyoscyamine b Rocuronium c Succinylcholine d…
3. What are the most common drug interactions with warfarin?
1. EXPLAIN THE RECEPTOR THEORY AND THE FOUR RECEPTOR FAMILIES. WHAT CLASS OF MEDICATION IS VERAPAMIL, AND HOW DOES IT WORK 2. WHAT KEY TEACHING POINTS WILL THE NURSE PROVIDE TO THE PATIENT REGARDING THIS MEDICATION?
2) Laura felt sick at a party last night after taking 3,4 methylenedioxymethamphetamine (MDMA), otherwise known as “ecstasy”. Despite drinking a lot of water, when she came home and went to sleep, she could not wake up the following morning. Out of concern, her friends brought her to a local hospital for evaluation. The ER doctor ordered a series of blood tests. The results are in the table. a. Write down some of your observations about Laura’s test results. b. MDMA may act as an anti-diuretic. Could this explain Laura’s test results? Why or why not? c. Why is Laura’s condition dangerous to her cells? d. Describe one way you could treat Laura’s condition.

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