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Using the web, find an antidote for cyanide and describe its molecular function


Using the web, find an antidote for cyanide and describe its molecular function

Step 1

Exposure to different forms of cyanide results in cyanide poisoning. Compounds like hydrogen cyanide and various salts contain toxic forms of cyanide. Exposure to fires, plant intoxication, drugs, and industrial accidents may result in cyanide poisoning.

Step 2

The antidote for cyanide and its molecular function are:

The conventional method of cyanide treatment is decontamination with specific treatment.In the case of smoke inhalation, the efficiency of antidotes and safety should be considered.Decontamination should be done on the route of poisoning. Several antidotes of cyanide poisoning are available. Cobalt compounds, Sodium thiosulfate, methemoglobin forming compounds efficiently act by transforming cyanide to the non-toxic substances or forming complex compounds.

Nitrates convert hemoglobin to Methemoglobin form by oxidizing hemoglobin’s iron  to the ferric form. Cyanide binds to the Methemoglobin and forms a compound, cyanmethemoglobin and releases cyanide from the cytochrome oxidase.

Sodium thiosulfate is very efficient but it acts with delay. In  body a mitochondrial enzyme, rhodanese uses thiosulfate as its substrate and neutralizes its effect. But this reaction occurs slowly in the body that is why thiosulfate is used with nitrates.

Step 3

 Methemoglobin forming compounds convert hemoglobin to methemoglobin. Methemoglobin impairs oxygen delivery to the tissues or various organs of the bo...

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